Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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ОРГАНИЗАЦИОННЫЕ ОСНОВЫ СКРИНИНГА КОЛОРЕКТАЛЬНОГО РАКА В МИРОВОЙ МЕДИЦИНСКОЙ ПРАКТИКЕ. ОБЗОР ЛИТЕРАТУРЫ
Автор (лар): Жолмурзаева Р.С
Актуальность. Рак ободочной и прямой кишки (колоректальный) является третьим по распространенности раком в мире. Он поддается скринингу, так как скрининговое исследование может быть осуществлено на предраковых, латентных, ранних и излечимых стадиях. При скрининге колоректального рака могут использоваться прямые или непрямые методы, применяемые произвольно или в структуре организованных программ. Большинство случаев колоректального рака диагностируется в возрасте старше 60 лет. Большинство программ скрининга относятся к лицам в возрасте 50-75 лет.
Цель обзора – Анализ подходов и р...
Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 13-24

MODERN TENDENCY IN TREATMENT OF PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY. LITERARY REVIEW
Relevance: Carrying out of intensive therapy at severe traumatic brain injury is a complex of measures aimed on saving of the brain tissues and maintaining its functions. To achieve this goal, it is necessary to do timely diagnostics and monitoring of critical parameters - intracranial pressure and cerebral perfusion pressure; pathogenetically based therapy and nutritional support for critically ill patients.
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera...
Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 5-12

ЛЕЧЕНИЕ ПОПЕРЕЧНОГО ПЛОСКОСТОПИЯ С HALLUX VALGUS ПРИ I и II ТИПЕ РАСПЛАСТАННОСТИ СТОПЫ
Введение. Статическая деформация переднего отдела стопы составляет до 80% среди ортопедической патологии стопы у взрослых. Патология вызывает значительное нарушение биомеханики всей нижней конечности, сопровождаясь болью в переднем отделе стопы, затруднение в подборе и ношении обуви, значительно снижает трудоспособность и качество жизни пациента. В связи с этим разработка технологии лечения статической деформации переднего отдела стопы, предусматривающей устранение Halluxvalgus, metatarsusprimavarus и плантарную девиацию центральных лучей стопы остается не полностью решенной и актуальной п...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 80-90

АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ ШИГЕЛЛ НА СОВРЕМЕННОМ ЭТАПЕ
Введение. Одна из больших проблем практического здравоохранения на современном этапе – это рост антибиотикорезистентности шигелл к тем антибактериальным препаратам, которые широко сегодня используются в их лечении.
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 74-79

RADIATION-INDUCED KI-67 PROLIFERATION IN THE SMALL INTESTINE OF RATS
Introduction. It is known that Hiroshima and Nagasaki were target of the first atomic bombs in the history of mankind. As a result, the population of Japanese cities was exposed to internal and external irradiation. Numerous authors maintain that primary neutron-activated radionuclides are chemical elements 56Mn and 60Co. Herewith, 56Mn was determined the dominant role of neutrons induced by β-radiation during the first few hours after the atomic bombing. The systemic access in estimation of Кi-67 marker in radiosensitive small intestine defining the functional state and the interrelation of s...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 63-73

CLINICAL - ORIENTED TECHNOLOGIES OF QUALITY ASSURANCE ORTHOPEDIC TREATMENT: COMPARATIVE EVALUATION PHYSICAL AND MECHANICAL PROPERTIES OF ACRYLIC PLASTICS POLYMERIZED WITH COLD TEMPREATURE
Автор (лар): Янишен И.В.
Introduction. Plastics of cold polymerization are using in dentistry to repair (rebase) dentures, repair of prostheses, the manufacture of temporary prostheses, tires on parodontal diseases, models, and other.
Manufacturer of removable prosthesis consists of many stages. The first is impression, after that there will be some technological stages in the dental laboratory. These includes obtaining the model, setting the teeth, making a wax model, making gypsum model in the dental ditch and removing, decoction of wax, and then filling the resulting space with forming material for th...
Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 60-71

THE MODERN VIEW PREMATURE BIRTH
Автор (лар): Жұмақанова К.С.
Premature birth is one of the topical problems in obstetrics and gynecology, also in perinatology, because premature infants account 60-70% of perinatal illness and mortality. But many aspects of premature birth problem is debatable and need further research. Using in full volume the known methods of research’s diagnostic opportunities and new medicine technologies will help to resolve this problem.
Despite the wide range of existing prediction methods, the presence of the selected biomarkers sensitivity used in this test time is not high enough and in the order 40-60%, so about ...
Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 39-49

MORPHOLOGICAL CHANGES INDUSED LUNG IINDUSTRIAL CHRYSOTILE FREE OF DUST
The respiratory organs directly interact with atmospheric air and this fact leads to the penetration of such harmful substances as gaseous fluid, fog, smoke, dust and aerosols into the lungs. And dust is the most harmful factor of the air pollution in the contemporary industrial production and the development of subsequent of the pulmonary dysfunction.
The morphological method of studying of the bronchial - pulmonary system is one of the basic criteria of evaluation of pathogenic properties of above-mentioned harmful substances. The method out is applied during the hygienic rate-setting ...
Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 30-38

THE MODERN UNDERSTANDING OF THE MOLECULAR MECHANISMS OF METFORMIN ACTION
There view deals with the analysis of the molecular
mechanism of the effect of metformin, the antidiabetic drug widely applied all
over the world. In addition to the hypoglycemic effect, metformin was
discovered to have several pleiotropic actions, particularly antitumor. The
effect of metformin on proliferation of cancer cells is related to activation
of AMP-sensitive kinase and suppression of mTOR, which plays an
important role in regulation of cellular growth. Glucose drop by metformin was
caused by its ability to suppress gluconeogenesis in liver t...
Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 19-29

CROSS-SECTIONAL STUDIES IN HEALTH SCIENCES
In this paper we present basic principles of planning and carrying out cross-sectional studies in health sciences as well as analyzing the data collected in these studies. We present practical examples of sample size and effect measures calculation for cross-sectional studies using online calculators and Epi Info software. Examples of studies using cross-sectional design from international peer-reviewed literature are also presented. This article provides general introduction to cross-sectional studies and does not substitute specialized literature in clinical epidemiology.
Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 5-18