Проанализированы генетические варианты, выделенные из полных геномов и экзомов и показавшие ассоциацию с развитием гипертонии, ожирением и диабетом по обоим алгоритмическим предикторам патогенности мутаций PolyPhen2 и SIFT. Обнаружено семь генетических вариантов GHRL (rs4684677), MTHFR &... Толығырақ
Целью обзора было изучение исторических аспектов проблемы очищения кишечника, выбора оптимальных способов лаважа и переносимости его пациентами.
Методы исследования. В данном обзоре рассмотрена эффективность различных методов лаважа, подготовки больного перед эндоскопическим исследованием и операцией. Проведён анализ 77 литературных источников с результатами изучения данной проблемы.
Результаты. Си... Толығырақ
В последние годы активно изучается возможность применения витаминов группы В при сосудистых и ней родегенеративных заболеваниях. Дефицит витаминов В6, В12, В9, возникший в результате особенностей диеты и нарушения абсорбции, признан одним из основных факторов развития гипергомоцистеинемии. Установлено, что применение препа... Толығырақ
Introduction. Intensive training in a medical university and responsibility before a chosen profession is often accompanied by psychological disorders. Numerous studies show the prevalence of depression, anxiety and somatoform disorders among students of medical specialties and according to the results of many studies are observed in almost 1/3 of the students.
The aim of the study was to measure the prevalence of somatoform disorders, anxiety and depression among foreign students enrolled in a medical univ...
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Introduction: At the present stage, according to the data of the transatlantic consensus (TASC II 2007 USA), about 90% of amputations of the lower limbs are performed around the world in view of the critical lower limb ischemia (CLLI). The most common diseases with CLLI with concomitant CHF are aorto-iliac segment lesions. In the treatment of lesions of the arteries of the aorto-iliac segment, surgical methods of treatment (shunting and endovascular methods of treatment) are used in most cases. In case of impossibility of direct...
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Introduction: One of the most frequent localizations of arterial occlusive diseases leading to the loss of the limb is the femoropopliteal segment. In the treatment of arterial lesions in the femoropopliteal segment, surgical methods of treatment (shunting and endovascular methods of treatment) are used in most cases. If it is not possible to conduct direct revascularization operations, this category of patients has a high risk of limb amputation at the hip level. In case of femoropopliteal occlusion, the viability of the limb d...
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Introduction. In recent decades, the worldwide increase in the incidence of colorectal cancer (further on CRC) is noted. A serious complication of CRC is perforation of the tumor or rupture of the intestinal wall proximal to the neoplasm. Prospects for improving the results of treatment of complicated colorectal cancer require the definition of conditions and the creation of an optimal algorithm for using surgical techniques of restoring the intestinal passage in combination with a complex pathogenetic approach, restoring the di...
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Background: prostate cancer holds second position out of all cancer morbidity among the world male population. At the same time, taking into account the female population, incidence of prostate cancer is on the fourth place, yielding its position to lung cancer, breast cancer and colorectal cancer. Prostate cancer is most common in the developed world, for which long life expectancy is characteristic, but it is less common in Asian countries, where it locates in the sixth place after cancers of other localizations: lung, stomach, liver, colorectal cancer ...
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