ПОЛИМОРФИЗМ ГЕНА ИЛ10 В ПОЛОЖЕНИИ -1082G/A У БОЛЬНЫХ РОЖЕЙ
Целью данного исследования является выявление связи полиморфизма гена ИЛ10-1082 GA (rs1800896) с заболеванием рожей у лиц казахской национальности.
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ... Толығырақ
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 34-45
ИЗМЕНЕНИЯ В ПЛАЗМЕ ТРИЙОДТИРОНИНА, ТИРОКСИНА И ТИРЕОТРОПНОГО ГОРМОНА ПОСЛЕ ОБЛУЧЕНИЯ 131 I У НОВОРОЖДЕННЫХ КРЫС, СОДЕРЖАВШИХСЯ НА ЙОДОДЕФИЦИТНОМ ПИТАНИИ
Background: Human thyroid gland is generally regarded as a relatively low-risk organ in terms of developing radiation-induced tumorigenesis. However, a rapid increase in the incidents of thyroid cancer after the Chernobyl nuclear reactor accident in 1986 provided additional insight into the risk of thyroid cancer. Three key risk factors have been identified to be involved in this increase: (1) internal irradiation from 131I fallout, (2) young age, and (3) a low-iodine diet. Our previous study demonstrated that the thyroid radiation dose was highest in the newborn rats f...
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2016 жыл | Шығарылым: 3 | Беттер: 26-33
СРАВНЕНИЕ КОЛИЧЕСТВЕННЫХ ДАННЫХ ДВУХ ПАРНЫХ ВЫБОРОК С ИСПОЛЬЗОВАНИЕМ ПРОГРАММНОГО ОБЕСПЕЧЕНИЯ STATISTICA И SPSS: ПАРАМЕТРИЧЕСКИЕ И НЕПАРАМЕТРИЧЕСКИЕ КРИТЕРИИ
В настоящей работе представлены общие сведения об использовании парного критерия Стьюдента, непараметрического критерия Вилкоксона и критерия знаков для сравнения количественных признаков парных выборок. Описан алгоритм расчета данных критериев с использованием программного обеспечения Statistica 10 и SPSS 20 и представлена интерпретация результатов расчетов. Настоящая статья призвана дать общие сведения об использовании парного критерия Стьюдента, парного критерия Вилкоксона и критерия знаков, и не заменяет прочтения специализированной литературы по статистике и клинической эпидемиологии.
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2016 жыл | Шығарылым: 3 | Беттер: 5-25
СРАВНИТЕЛЬНЫЙ АНАЛИЗ РАСПРЕДЕЛЕНИЯ РАБОЧЕГО ВРЕМЕНИ У СОТРУДНИКОВ ОТДЕЛЕНИЙ ХИРУРГИЧЕСКОГО ПРОФИЛЯ ПРИ ИСПОЛЬЗОВАНИИ МЕДИЦИНСКОЙ ИНФОРМАЦИОННОЙ СИСТЕМЫ
2016 жыл | Шығарылым: 2 | Беттер: 150-161
ПРИВЕРЖЕННОСТЬ ЗДОРОВОМУ ОБРАЗУ ЖИЗНИ УЧАЩИХСЯ СРЕДНИХ ШКОЛ И КОЛЛЕДЖЕЙ
Здоровье человека является одной из глобальных проблем современного общества, выходящих за рамки медицинской науки и практики. В последние годы отмечается рост заболеваемости среди молодых людей. Одной из причин подобной тенденции является отсутствие у молодых людей достаточного воспитания и практического опыта ведения здорового образа жизни. Молодежь удовлетворена своим здоровьем и готова вести здоровый образ жизни, но при этом общей культуры введения здорового образа жизни в сознании молодых людей еще не сформирована.
Цель исследования – изучения социальных и личностных аспектов молоды... Толығырақ
Цель исследования – изучения социальных и личностных аспектов молоды... Толығырақ
2016 жыл | Шығарылым: 2 | Беттер: 139-149
ҚАНТ ДИАБЕТІ КЕЗІНДЕГІ ТАБАННЫҢ ІРІҢДІ-НЕКРОТИКАЛЫҚ ЗАҚЫМДАЛУЫНЫҢ ХИРУРГИЯЛЫҚ ЕМІ
2013 жыл | Шығарылым: 2 | Беттер: 32-34
РАДИАЦИЯЛЫҚ ӘСЕРГЕ ТАП БОЛҒАН АДАМДАРДЫҢ ІШІНДЕ, ҚАН АЙНАЛЫМ ЖҮЙЕСІ АУРУЛАРЫН БОЛЖАУ ТӘСІЛДЕРІ, ЕРТЕ ДИАГНОСТИКАЛАУ, ЕМДЕУ ЖӘНЕ ПРОФИЛАКТИКА
2013 жыл | Шығарылым: 2 | Беттер: 22-24
MORTALITY FROM CARDIOVASCULAR DISEASES IN THE POPULATION OF KAZAKHSTAN EXPOSED TO RADIATION
2013 жыл | Шығарылым: 2 | Беттер: 16-21
ANALYSIS OF RADIATION REACTIONS OF SKIN AFTER HYPOFRACTIONATED RADIATION THERAPY OF BREAST CANCER
Background: In the Republic of Kazakhstan, breast cancer takes a leading position among all malignant neoplasms in women. Radiation therapy is a standard and obligatory component of complex treatment of breast cancer. Daily fractions use of 2 Gy to a total focal dose of 50 Gy is the traditional standard scheme for radiotherapy treatment. However, due to the increase in the number of detected diseases at an early stage, approaches to the treatment of breast cancer have changed in recent years. Acute radiation skin reactions are one of the most frequent side effects of this...
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2018 жыл | Шығарылым: 6 | Беттер: 114-120
ORGANIZATION ASPECTS OF THE PALLIATIVE CARE SYSTEM FOR CANCER PATIENTS BASED ON THE OPINION OF RELATIVES AND CLOSEST INCURABLE PATIENTS
neoplasms. Kazakhstan is in its infancy a palliative care service for oncology patients. The lack of rehabilitation assistance significantly worsens the quality of life of patients. In this regard, it is supposed to constantly improve the professional level of specialists in the field of rehabilitation, prevention and palliative care for patients with malignant tumors. Today, patients with malignant neoplasms undergo medical and social rehabilitation. The absence of the psychological and social aspects mentioned above also indicates that these conditions are resolved separately from medical in...
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2018 жыл | Шығарылым: 6 | Беттер: 121-130
PARKINSON'S DISEASE AND THE PROBLEMS OF TREATMENT OF TREATED STATIONARY CASES IN THE STATE MEDICAL UNIVERSITY HOSPITAL OF SEMEY FOR 2013-2018
Relevance: The article presents the main problems that a doctor encounters in the neurology department during diagnosis and treatment of Parkinson's disease. Parkinson's disease (PD) is a chronic progressive neurodegenerative disease, the incidence of which is steadily increasing. The notion of PD as an exclusively purely motor disorder has undergone significant changes.
Purpose: The goal was to analyze the clinical and diagnostic approaches of treated cases of PD and the basic inpatient treatment scheme for this pathology, as well as to identify existing problems of tre... Толығырақ
Purpose: The goal was to analyze the clinical and diagnostic approaches of treated cases of PD and the basic inpatient treatment scheme for this pathology, as well as to identify existing problems of tre... Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 131-137
THE OPTIMIZATION OF TREATMENT OF ESSENCIAL ARTERIAL HYPERTENSION IN EAST KAZAKHSTAN
Introduction.Despite the successes achieved in the treatment of essential hypertension (AH), the problem of treatment of resistant hypertension remains urgent.
In this regard, in many countries around the world, innovative non-drug method of sympathetic denervation of renal arteries using high frequency currents has been widely spread.
Aim. To determine efficacy of sympathetic denervation of renal arteries for the course of resistant hypertension according to the materials of the cardiological department of the University Hospital.
Materials and methods. 86 patients ... Толығырақ
In this regard, in many countries around the world, innovative non-drug method of sympathetic denervation of renal arteries using high frequency currents has been widely spread.
Aim. To determine efficacy of sympathetic denervation of renal arteries for the course of resistant hypertension according to the materials of the cardiological department of the University Hospital.
Materials and methods. 86 patients ... Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 138-142
ABOUT THE OBVIOUS EFFICIENCY AND REAL PREDICTIONS OF THE APPLICATION OF ANTI-FNO DRAG «FLAMMEGIS» IN CHRONIC INFLAMMATORY DISEASES OF THE INTESTINE
Introduction: Chronic inflammatory bowel disease (HIBD), namely ulcerative colitis (UC) and Crohn's disease (CD) are among the most severe diseases of the digestive system.
Aim: to study the effeciency of infliximab biosimilar "Flammegis" in chronic inflammatory bowel disease.
Materials and methods. Biological therapy (BT) was carried out under the conditions of the gastroenterology department of the University Hospital of Semey State Medical University according to the developed and generally accepted methodology: the Flammegis intrav... Толығырақ
Aim: to study the effeciency of infliximab biosimilar "Flammegis" in chronic inflammatory bowel disease.
Materials and methods. Biological therapy (BT) was carried out under the conditions of the gastroenterology department of the University Hospital of Semey State Medical University according to the developed and generally accepted methodology: the Flammegis intrav... Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 143-149