МОРФОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ ЛЕГКИХ ПРИ ВОЗДЕЙСТВИИ ПРОМЫШЛЕННОЙ ХРИЗОТИЛСОДЕРЖАЩЕЙ ПЫЛИ
Органы дыхания напрямую взаимодействуют с атмосферным воздухом и это ведет к проникновению таких вредных субстанций, как газ, туман, дым, пыль и аэрозоли в легкие. Пыль является наиболее важным фактором загрязнения воздуха на современном индустриальном предприятии и развитии последующих дисфункций легких.
Морфологический метод исследования бронхиально-легочной системы является критерием оценки патогенных свойств вышеперечисленных вредных веществ. Этот метод применяется при гигиеническом нормировании промышленных аэрозолей.
В последние годы отмечается рост про...
Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 30-38
СОВРЕМЕННОЕ ПРЕДСТАВЛЕНИЕ О МОЛЕКУЛЯРНЫХ МЕХАНИЗМАХ ДЕЙСТВИЙ МЕТФОРМИНА
Обзор посвящен анализу молекулярных механизмов действия метформина, широко применяемого во всем мире, антидиабетического средства. Кроме гипогликемического действия у метформина обнаружен ряд плейотропных эффектов, в частности противоопухолевый. <span style="border-width: 1pt; border-color: windowtext;">Эффект метформина на пролиферацию раковых клеток связан с активацией AMPK и угнетением </span><span style="border-width: 1pt; border-color: windowtext;">mTOR</span><span style="border-width: 1pt; border-color: windowtext;">, который иг...
Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 19-29
ПОПЕРЕЧНЫЕ (ОДНОМОМЕНТНЫЕ) ИССЛЕДОВАНИЯ В ЗДРАВООХРАНЕНИИ
В настоящей работе представлены основные принципы планирования, проведения и статистической обработки данных поперечных (одномоментных) исследований в здравоохранении. Приведены практические примеры расчета размера выборки и оценки связи между факторами риска с помощью онлайн-калькуляторов и пакета для обработки эпидемиологических данных Epi Info. Авторы представляют практические примеры использования поперечных исследований в литературе, а также достоинства и недостатки данного типа исследований. Настоящая статья призвана дать общие сведения о поперечных исследованиях, и не заменяет п...
Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 5-18
ХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ ВНУТРИМОЗГОВЫХ КРОВОИЗЛИЯНИЙ У БЕРЕМЕННЫХ ЖЕНЩИН
Возникновение неотложных нейрохирургических
состояний у беременных женщин является сложной мультидисциплинарной проблемой,
для решения которой требуется участие специалистов нескольких смежных
специальностей.
Толығырақ
2015 жыл | Шығарылым: 1 | Беттер: 77-80
МОДЕЛЬ УПРАВЛЕНИЯ МОТИВАЦИЕЙ МЕДИЦИНСКОГО ПЕРСОНАЛА НА ПРИМЕРЕ РЕГИОНАЛЬНОГО ОНКОЛОГИЧЕСКОГО ДИСПАНСЕРА ГОРОДА СЕМЕЙ
В статье представлена модель мотивационного управления медицинским персоналом Регионального онкологического диспансера г. Семей, на базе которого находится кафедра онкологии и радиологии медицинского университета имени д.м.н., профессора Д.Р. Мусинова и проходят обучение по программе резидентура, магистратура, Phd докторантура. Мотивация персонала освещена в свете реализации Программы развития онкологической помощи на 2012-2016 года, включая развитие ядерной медицины. Создание высокоэффективных и мотивированных команд, в том числе и в лечебно-профилактических учреждениях, позволит повысить про...
Толығырақ
2015 жыл | Шығарылым: 1 | Беттер: 70-76
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
ASSESSMENT OF THE PROBABILITY OF DEVELOPING CARDIORENAL SYNDROME TYPE 2 DEPENDING ON POTENTIAL BIOMARKERS IN PEDIATRIC PATIENTS
2025 жыл | Шығарылым: 6 | Беттер: 21-29
MORPHO-GENETIC VARIABILITY IN MYOCARDIAL TISSUE AFTER SEPTAL MYECTOMY IN PATIENTS WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: A FOUR-CASE SERIES STUDY
2025 жыл | Шығарылым: 6 | Беттер: 30-37
CLINICAL EFFICACY OF SELECTIVE PLASMA FILTRATION (EVACLIO) IN CARDIOVASCULAR COMPLICATIONS: A CASE SERIES FROM THE HEART CENTER KAZAKHSTAN
2025 жыл | Шығарылым: 6 | Беттер: 38-46
COMMENTS ON 2017 EUROPEAN GUIDELINES FOR THE MANAGEMENT OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS PRESENTING WITH ST-SEGMENT ELEVATION
Updated European guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation were published in 2017. All the new and changed recommendations was analysed in order to investigate the possibility of their application in our country.
Objective: to reveal essential evidence-based updated points of the 2017 guidelines that can be implemented in the settings of Kazakhstan health care system.
Materials and methods: the first stage of the review was performing a comparative analysis of old (2012) and updated versions ... Толығырақ
Objective: to reveal essential evidence-based updated points of the 2017 guidelines that can be implemented in the settings of Kazakhstan health care system.
Materials and methods: the first stage of the review was performing a comparative analysis of old (2012) and updated versions ... Толығырақ
2017 жыл | Шығарылым: 5 | Беттер: 99-112
ORGANIZATION OF PRIMARY HEALTH CARE FOR TYPE II DIABETES PATIENTS IN SELECTED OECD COUNTRIES
In this literature review we present international experience in organization of primary health care for Type II diabetic patients in different countries at various stages of economic development.
This is a semisystematic review of literature published in English language literature. Article search was performed using the following key words: «Type II diabetes», primary health care”, “OECD” using PubMed, Medline Complete, Wiley Online Library, SpringerLink, Google scholar, eLibrary, published from 2010 to 2017 годы. Also we studied program documents of the International Diabetic ... Толығырақ
This is a semisystematic review of literature published in English language literature. Article search was performed using the following key words: «Type II diabetes», primary health care”, “OECD” using PubMed, Medline Complete, Wiley Online Library, SpringerLink, Google scholar, eLibrary, published from 2010 to 2017 годы. Also we studied program documents of the International Diabetic ... Толығырақ
2017 жыл | Шығарылым: 5 | Беттер: 88-98
ESTIMATING THE PREVALENCE OF RISK FACTORS FOR PROGRESSION OF CHRONIC KIDNEY DISEASE IN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS
Introduction: effective prevention of chronic kidney disease is possible on the basis of early detection of risk factors for its development, elaboration of measures for their stratification, and searching for optimal diagnostic markers.
Aim: determination of risk factors prevalence for progression of chronic kidney disease in patients with chronic glomerulonephritis.
Materials and methods. The design of the study is a cross-sectional sociological study.116 patients undergoing treatment in nephrological department of the Hospital of nephrology, internal ... Толығырақ
Introduction: effective prevention of chronic kidney disease is possible on the basis of early detection of risk factors for its development, elaboration of measures for their stratification, and searching for optimal diagnostic markers.
Aim: determination of risk factors prevalence for progression of chronic kidney disease in patients with chronic glomerulonephritis.
Materials and methods. The design of the study is a cross-sectional sociological study.116 patients undergoing treatment in nephrological department of the Hospital of nephrology, internal ... Толығырақ
2017 жыл | Шығарылым: 5 | Беттер: 76-87
COMPARISON OF CLINICAL FEATURES OF PANIC DISORDER PATIENTS WITH AND WITHOUT FAMILY HISTORY OF PSYCHIATRIC DISORDERS
Introduction: The large goal of this study elucidates the cause of panic disorder, and medical people carry out the fundamental treatment and prevention for the disorder.
Purpose: One aim of this study was to investigate the diagnosis of psychiatric disorders (including panic disorder) in first-degree relatives of panic disorder patients. Another aim of this study was to examine the age at the onset of the first panic attack and the number of symptoms at onset in panic disorder patients in order to better understand the in fluence of family history of psychiatric disorders (i... Толығырақ
Purpose: One aim of this study was to investigate the diagnosis of psychiatric disorders (including panic disorder) in first-degree relatives of panic disorder patients. Another aim of this study was to examine the age at the onset of the first panic attack and the number of symptoms at onset in panic disorder patients in order to better understand the in fluence of family history of psychiatric disorders (i... Толығырақ
2017 жыл | Шығарылым: 5 | Беттер: 67-75
THE INFLUENCE OF PREGNANCY-ASSOCIATED PLASMA PROTEIN А (РАРР-А) ON INTRAUTERINE GROWTH RESTRICTION
Introduction: the search of methods enabling to predict fetal growth impairment is an important issue for modern obstetrics. Pregnancy-associated plasma protein А (РАРР-А) is considered to be one of the predictors of fetal chromosomal mutations. The associations between reduced РАРР-А levels in first pregnancy trimester and the development of intrauterine growth restriction (IUGR) is being extensively studied over the last years. The current normal range of РАРР-А in Kazakhstan is considered to be 0,5-2,05.
Aim: to study the associations between РАРР-А levels in first pre... Толығырақ
Aim: to study the associations between РАРР-А levels in first pre... Толығырақ
2017 жыл | Шығарылым: 5 | Беттер: 55-66