ВЛИЯНИЕ ОТДАЛЕННЫХ ПОСЛЕДСТВИЙ ОСТРОГО ГАММА-ИЗЛУЧЕНИЯ И ЭМОЦИОНАЛЬНОГО СТРЕССА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ КОСТНОГО МОЗГА И ТИМУСА
В раннем периоде общего адаптационного синдрома снижается масса тимуса, повышается количество лимфо-идных клеток, в последующей стадии в тимусе возрастает масса и нормализуется число лимфоидных клеток. Во всех фазах адаптационного синдрома в костном мозге происходит повышение лимфоидных клеток.
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 62-65
ОТДАЛЕННЫЕ ЭФФЕКТЫ РАЗНОЙ ДОЗЫ ГАММА-ИЗЛУЧЕНИЯ НА ЛИМФОИДНЫЕ ОРГАНЫ ИММУНОГЕНЕЗА
В отдаленном периоде после сублетального и фракционированного действия гамма-излучения в тимусе и лим-фатических узлах тонкого кишечника снижены количества лимфоидных клеток. В тимусе и селезенке определяется атрофия, в лимфатических узлах тонкого кишечника - сниженный лимфоидный индекс и лимфоидных клеток.
В отдаленном периоде после воздействия малой дозы гамма-излучения отмечается атрофия тимуса и перерас-пределение лимфоидных клеток из тимуса и лимфатических узлов тонкого кишечника в костный мозг и селезенку.
Толығырақ
В отдаленном периоде после воздействия малой дозы гамма-излучения отмечается атрофия тимуса и перерас-пределение лимфоидных клеток из тимуса и лимфатических узлов тонкого кишечника в костный мозг и селезенку.
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 49-53
DENTAL STATUS OF PATIENTS DURING THE SUPPORTIVE CARE AT ANTINEOPLASTIC CHEMOTHERAPY FOR BREAST CANCER
Two groups were studied in a comparative aspect – 98 women with breast cancer during the courses of adjuvant chemo-therapy: the first was comprised of 26 patients who used their conventional means for oral hygiene; the second included 72 patients, who received the complex of therapeutic and preventive measures of supportive care. Dental toxicity was observed in 84.6-96.2 %, and has grown with the increase of the cycles of chemotherapy, reaching a maximum value on the V cycle of treatment. It is shown that the application of the developed complex significantly reduces the manifestations of ...
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 35-39
ДАННЫЕ СКРИНИНГА ПАТОЛОГИИ ЩИТОВИДНОЙ ЖЕЛЕЗЫ У ЖИТЕЛЕЙ РАЙОНОВ, ПОДВЕРГШИХСЯ РАДИАЦИОННОМУ ОБЛУЧЕНИЮ
В статье приведены данные, полученные в результате скрининга населения районов, подвергшихся радиационному облучению. Целью исследования было выявление частоты и особенностей патологии щитовидной железы у жителей районов Павлодарской и Восточно-Казахстанской областей, подвергшиеся радиационному облучению. Обследовано 1783 человека. Диффузный эутиреоидный зоб диагностирован в 32,97% случаев, колло-идно-узловой зоб у 13,60% обследованных, аутоиммуный тиреоидит у 52,96%, в 2,4% случаев наблюдался много-узловой зоб. Анализ функционального состояния щитовидной железы пока...
Толығырақ
2014 жыл | Шығарылым: 3 | Беттер: 22-25
МОДЕЛИРОВАНИЕ САХАРНОГО ДИАБЕТА 2 ТИПА ДЛЯ ИЗУЧЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ С АНТИДИАБЕТИЧЕСКОЙ АКТИВНОСТЬЮ
Учитывая неуклонно возрастающее во всем мире число больных сахарным диабетом 2 типа, актуальной проблемой современной фармакологии продолжает оставаться разработка антидиабетических препаратов, обладающих высокой терапевтической активностью и имеющих более совершенный профиль безопасности. В связи с этим важное значение имеет моделирование сахарного диабета, позволяющее достоверно выявлять наличие той или иной фармакологической активности или новых деталей в механизме действия лекарственных средств. Модели сахарного диабета могут быть получены на различных видах животных ...
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 4-8
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
ASSESSMENT OF THE PROBABILITY OF DEVELOPING CARDIORENAL SYNDROME TYPE 2 DEPENDING ON POTENTIAL BIOMARKERS IN PEDIATRIC PATIENTS
2025 жыл | Шығарылым: 6 | Беттер: 21-29
MORPHO-GENETIC VARIABILITY IN MYOCARDIAL TISSUE AFTER SEPTAL MYECTOMY IN PATIENTS WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: A FOUR-CASE SERIES STUDY
2025 жыл | Шығарылым: 6 | Беттер: 30-37
CLINICAL EFFICACY OF SELECTIVE PLASMA FILTRATION (EVACLIO) IN CARDIOVASCULAR COMPLICATIONS: A CASE SERIES FROM THE HEART CENTER KAZAKHSTAN
2025 жыл | Шығарылым: 6 | Беттер: 38-46
HYPERHOMOCYSTEINEMIA AS A RISK FACTOR OF CARDIOVASCULAR DISEASES
Cardiovascular diseases are the leading cause of death. In this regard, the importance of the prevention problem increases, which is aimed at the identification and elimination of risk factors, which include elevated levels of homocysteine in the blood.
In recent years, actively studying the possibility of the use of B vitamins in vascular and neurodegenerative diseases. One of the main factors of hyperhomocysteinemia is the deficiency of vitamins B6, B12, B9 resulting from the features of the diet and impaired absorption. It was found that the use of preparations of B vitamins can reduc... Толығырақ
In recent years, actively studying the possibility of the use of B vitamins in vascular and neurodegenerative diseases. One of the main factors of hyperhomocysteinemia is the deficiency of vitamins B6, B12, B9 resulting from the features of the diet and impaired absorption. It was found that the use of preparations of B vitamins can reduc... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 129-144
MOLECULAR TYPE OF BREAST CANCER AS PROGNOSTIC FACTOR FOR METASTASIS
Introduction: The article provides an overview of the literature data on the peculiarities of metastasis of different subtypes of breast cancer (BC), which is characterized by heterogeneity, malignancy, early and rapid lymphatic and hematogenous metastasis. Modern studies have shown about the connection between the molecular type and localization of metastatic breast cancer.
Objective: Analysis of published data about the features of different molecular subtypes of breast cancer metastasis.
Materials and Methods: publications searched in the following databases: PubMed Med... Толығырақ
Objective: Analysis of published data about the features of different molecular subtypes of breast cancer metastasis.
Materials and Methods: publications searched in the following databases: PubMed Med... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 119-128
ASSOCIATION OF POLYMORPHISMS OF GENES OF IL1B (RS1143627), IL10 (RS1800896), IL17А (RS 2275913, RS8193036) WITH INFECTIOUS DISEASES INCLUDING ERYSIPELAS
The investigate of polymorphism of cytokine genes is an important in pathogenesis of many diseases and in identifying susceptibility to them. Knowledge of their role in the pathogenesis of many diseases, particularly infectious diseases are permits, on the one hand, to predict risk of disease or severity of its flow, on the other - to pick up individually specific therapy for a particular patient.
Despite the fact that to date, in the literature there are a significant number of studies that found an association between polymorphisms of cytokine genes and susceptibility to infectious dis... Толығырақ
Despite the fact that to date, in the literature there are a significant number of studies that found an association between polymorphisms of cytokine genes and susceptibility to infectious dis... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 104-118
STRUCTURE AND FREQUENCY OF CHILDBIRTH COMPLICATIONS OF MACROSOMIA
The relevance study macrosomia’s problem lies in the fact that the great mass of the fetus at birth is associated with increased frequency of obstetric pathology, which in turn leads to an increase in perinatal mortality and have a negative impact on the further development of children [11,12,13,14,15].
Research objectives: Determine the structure of childbirth complications and the frequency at macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digits ... Толығырақ
Research objectives: Determine the structure of childbirth complications and the frequency at macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digits ... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 93-103
DIAGNOSTIC VALUE OF MACROSOMIAS PREDICTOR
Determination of the expected weight of the fetus and the diagnosis of complications in childbirth remains debated issue. To select the optimum tactics of labor with large fetus and reduce the complications accurate methods of prenatal prediction of macrosomia are required.
Research objectives: to evaluate the diagnostic value of ultrasound measurement of abdominal circumference, as a predictor of macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digit... Толығырақ
Research objectives: to evaluate the diagnostic value of ultrasound measurement of abdominal circumference, as a predictor of macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digit... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 84-92