МИОКАРД ИНФАРКТІМЕН БІРІККЕН ЦЕРЕБРОВАСКУЛЯРЛЫ ПАТОЛОГИЯСЫ БАР НАУҚАСТАРДАҒЫ HLA АНТИГЕНДЕРІНІҢ БӨЛІНУІ
Всего обследовано 25 больных с инфарктом миокарда сочетанной с цереброваскулярной патологией. Кон-трольную группу составили доноры здоровые лица 442 человек. Типирование антигенов гистосовместимости HLA I класса проводились в стандартном двухступенчатом микролимфоцитоксическом тесте. Иммуногенетическими маркерами повышенного риска заболеваемости инфаркта миокарда при сочетании цереброваскулярной патологией у казахов являются антигены HLA А1, А2, А9, В5, В7, В12, В35, В40 и гаплотипы А1/В12, А2/В12, А9/В12; у русских HLA А10, В5, В7, В17, В40; фенотип В7/В8 и гаплотипы А10/В5, А10/В7. Протектив...
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 23-26
Влияние радиационных и нерадиационных факторов риска на формирование заболева-ний системы кровообращения и методы их профилактики с позиции доказательной меди-цины
В статье представлен литературный обзор по проблеме изучения радиационных и нерадиационных факторов риска болезней системы кровообращения. Проведен анализ информации из баз данных по доказательной медицине по профилактическим и реабилитационным мероприятиям, включающим длительный и постоянный мониторинг путем проведения скрининговых обследований на местах
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2012 жыл | Шығарылым: 3 | Беттер: 20-23
ДОНОЗОЛОГИЧЕСКАЯ ДИАГНОСТИКА И ПРОФИЛАКТИКА БОЛЕЗНЕЙ СИСТЕМЫ КРОВООБРАЩЕНИЯ У ЛИЦ, ПОДВЕРГАВШИХСЯ ВОЗДЕЙСТВИЮ РАДИАЦИОННОГО ФАКТОРА, НА ОСНОВЕ ИЗУЧЕНИЯ ГЕННОГО ПОЛИМОРФИЗМА
В статье представлены принципы донозологической диагностики социально значимых болезней системы кровообращения на основе определения полиморфизма генов-кандидатов, определяющих уровень артериального давления, обмен гомоцистеина и метаболизм липидов. Исследование позволило установить высокую корреляци-онную связь гетерозиготных нарушений в отношении гена-кандидата AGT, предполагающую высокую степень наследования сосудистой патологии экспонированных радиацией родителей их потомками. Результаты ис-следований свидетельствуют о необходимости совершенствования системы длительного монитори...
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 18-20
К ПРОБЛЕМЕ ОРГАНИЗАЦИИ САМОСТОЯТЕЛЬНОЙ РАБОТЫ СТУДЕНТОВ
В статье рассматривается проблема организации самостоятельной работы студентов. Oриентация на СРС при хорошо организованном и научно обоснованном методическом обеспечении повышает качественные пока-затели образовательного процесса, дает совершенно новые возможности.
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2012 жыл | Шығарылым: 3 | Беттер: 15-17
ЛИТЕРАТУРНЫЙ ОБЗОР БАРЬЕРОВ ДОСТУПА МОЛОДЫХ ЛЮДЕЙ К МЕДИКО-СОЦИАЛЬНЫМ СЕРВИСАМ
2012 жыл | Шығарылым: 3 | Беттер: 14-15
RECTAL CANCER IN KAZAKHSTAN, 2005–2024: COMPONENT ANALYSIS OF INCIDENCE TRENDS IN THE CONTEXT OF SCREENING AND COVID-19
2025 жыл | Шығарылым: 5 | Беттер: 160-168
MAPPING THE RESEARCH LANDSCAPE: IONIZING RADIATION-INDUCED OXIDATIVE STRESS AND INFLAMMATION IN THE BRAIN – A BIBLIOMETRIC ANALYSIS
2025 жыл | Шығарылым: 5 | Беттер: 169-182
ASSOCIATION BETWEEN EXPOSURE TO IONIZING RADIATION AND THE DEVELOPMENT OF CARDIOVASCULAR DISEASES: A LITERATURE REVIEW
2025 жыл | Шығарылым: 5 | Беттер: 183-190
ADVANCES IN POTENTIAL BIOMARKERS FOR RHEUMATOID ARTHRITIS: SYSTEMATIC REVIEW
2025 жыл | Шығарылым: 5 | Беттер: 191-202
RISK FACTORS AND PREVALENCE OF URINARY INCONTINENCE AMONG WOMEN IN FOREIGN COUNTRIES. LITERATURE REVIEW
2025 жыл | Шығарылым: 5 | Беттер: 203-213
CLINICAL - ORIENTED TECHNOLOGIES OF QUALITY ASSURANCE ORTHOPEDIC TREATMENT: COMPARATIVE EVALUATION PHYSICAL AND MECHANICAL PROPERTIES OF ACRYLIC PLASTICS POLYMERIZED WITH COLD TEMPREATURE
Introduction. Plastics of cold polymerization are using in dentistry to repair (rebase) dentures, repair of prostheses, the manufacture of temporary prostheses, tires on parodontal diseases, models, and other.
Manufacturer of removable prosthesis consists of many stages. The first is impression, after that there will be some technological stages in the dental laboratory. These includes obtaining the model, setting the teeth, making a wax model, making gypsum model in the dental ditch and removing, decoction of wax, and then filling the resulting space with forming material for th... Толығырақ
Manufacturer of removable prosthesis consists of many stages. The first is impression, after that there will be some technological stages in the dental laboratory. These includes obtaining the model, setting the teeth, making a wax model, making gypsum model in the dental ditch and removing, decoction of wax, and then filling the resulting space with forming material for th... Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 60-71
THE MODERN VIEW PREMATURE BIRTH
Premature birth is one of the topical problems in obstetrics and gynecology, also in perinatology, because premature infants account 60-70% of perinatal illness and mortality. But many aspects of premature birth problem is debatable and need further research. Using in full volume the known methods of research’s diagnostic opportunities and new medicine technologies will help to resolve this problem.
Despite the wide range of existing prediction methods, the presence of the selected biomarkers sensitivity used in this test time is not high enough and in the order 40-60%, so about ... Толығырақ
Despite the wide range of existing prediction methods, the presence of the selected biomarkers sensitivity used in this test time is not high enough and in the order 40-60%, so about ... Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 39-49
MORPHOLOGICAL CHANGES INDUSED LUNG IINDUSTRIAL CHRYSOTILE FREE OF DUST
The respiratory organs directly interact with atmospheric air and this fact leads to the penetration of such harmful substances as gaseous fluid, fog, smoke, dust and aerosols into the lungs. And dust is the most harmful factor of the air pollution in the contemporary industrial production and the development of subsequent of the pulmonary dysfunction.
The morphological method of studying of the bronchial - pulmonary system is one of the basic criteria of evaluation of pathogenic properties of above-mentioned harmful substances. The method out is applied during the hygienic rate-setting ... Толығырақ
The morphological method of studying of the bronchial - pulmonary system is one of the basic criteria of evaluation of pathogenic properties of above-mentioned harmful substances. The method out is applied during the hygienic rate-setting ... Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 30-38
THE MODERN UNDERSTANDING OF THE MOLECULAR MECHANISMS OF METFORMIN ACTION
There view deals with the analysis of the molecular
mechanism of the effect of metformin, the antidiabetic drug widely applied all
over the world. In addition to the hypoglycemic effect, metformin was
discovered to have several pleiotropic actions, particularly antitumor. The
effect of metformin on proliferation of cancer cells is related to activation
of AMP-sensitive kinase and suppression of mTOR, which plays an
important role in regulation of cellular growth. Glucose drop by metformin was
caused by its ability to suppress gluconeogenesis in liver t... Толығырақ
mechanism of the effect of metformin, the antidiabetic drug widely applied all
over the world. In addition to the hypoglycemic effect, metformin was
discovered to have several pleiotropic actions, particularly antitumor. The
effect of metformin on proliferation of cancer cells is related to activation
of AMP-sensitive kinase and suppression of mTOR, which plays an
important role in regulation of cellular growth. Glucose drop by metformin was
caused by its ability to suppress gluconeogenesis in liver t... Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 19-29
CROSS-SECTIONAL STUDIES IN HEALTH SCIENCES
In this paper we present basic principles of planning and carrying out cross-sectional studies in health sciences as well as analyzing the data collected in these studies. We present practical examples of sample size and effect measures calculation for cross-sectional studies using online calculators and Epi Info software. Examples of studies using cross-sectional design from international peer-reviewed literature are also presented. This article provides general introduction to cross-sectional studies and does not substitute specialized literature in clinical epidemiology.
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2015 жыл | Шығарылым: 2 | Беттер: 5-18