HERPESVIRUS INFECTION IN CHILDREN IN THE ETIOLOGY OF HEMORRHAGIC VASCULITIS
2023 жыл | Шығарылым: 2 | Беттер: 160-165
ANALYSIS OF THE CONDUCT OF AN INDEPENDENT EXAMINATION AT THE POSTGRADUATE LEVEL DURING PANDEMIC
2023 жыл | Шығарылым: 2 | Беттер: 278-282
СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ РАЗВИТИЯ И МЕТОДОВ ДИАГНОСТИКИ БОЛЕЗНИ ГИРШПРУНГА. ОБЗОР ЛИТЕРАТУРЫ
2023 жыл | Шығарылым: 2 | Беттер: 216-224
EVALUATION OF THE EFFICACY 5-FLUOROURACIL ON ERECTILE FUNCTION IN PATIENTS UNDER SURGICAL TREATMENT OF BENIGN PROSTATE HYPERPLASIA
2023 жыл | Шығарылым: 2 | Беттер: 105-110
ANALYSIS OF THE STAFFING AND STRUCTURE OF THE AMBULANCE SERVICE IN THE REPUBLIC OF KAZAKHSTAN
2023 жыл | Шығарылым: 2 | Беттер: 143-149
МИДЫҢ ИНТРАКРАНИАЛДЫ АНЕВРИЗМАЛАРЫНЫҢ ОТБАСЫЛЫҚ ФОРМАЛАРЫНЫҢ ГЕНЕТИКАЛЫҚ ҚАУІП ФАКТОРЛАРЫ. ӘДЕБИ ШОЛУ.
2021 жыл | Шығарылым: 5 | Беттер: 185-193
ТИІМДІ ШЕШІМДЕР ҚАБЫЛДАУДАҒЫ ЖАҢА МЕДИЦИНАЛЫҚ ТЕХНОЛОГИЯЛАРДЫҢ ДАМУЫ МЕН ӘСЕРІНІҢ РӨЛІ. ӘДЕБИ ШОЛУ
2021 жыл | Шығарылым: 5 | Беттер: 174-184
ҚАЗАҚСТАН РЕСПУБЛИКАСЫНДА ДЕМЕНЦИЯНЫҢ ТАРАЛУЫ ТУРАЛЫ ТЕОРИЯЛЫҚ БОЛЖАМЫ
2021 жыл | Шығарылым: 5 | Беттер: 161-173
СЕМІЗДІК, ҚАНТ ДИАБЕТІ ЖӘНЕ АРТЕРИЯЛЫҚ ГИПЕРТЕНЗИЯ - ҚАЗІРГІ ҚОҒАМНЫҢ ЖАҺАНДЫҚ МӘСЕЛЕЛЕРІ. ӘДЕБИЕТКЕ ШОЛУ
2021 жыл | Шығарылым: 5 | Беттер: 149-160
IMPACT OF ERYTHROCYTES ANTIGENS ON DEVELOPMENT OF LIVER CIRRHOSIS
Introduction. High rates of prevalence and mortality of liver cirrhosis, it’s late clinical manifestation, disadvantages of liver biopsy highlight the background points of our research.
Aim. Research of erythrocytes’ antigens profile in patients with liver cirrhosis of Kazakh and Russian ethnical groups.
Materials and Methods: One hundred and forty patients with liver cirrhosis and 272 relatively healthy participants of both of nationalities were involved into research. АВ0, MNS, P1, CDE systems of erythrocytes of venous blood were investigated. For the comparison of the frequenc... Толығырақ
Aim. Research of erythrocytes’ antigens profile in patients with liver cirrhosis of Kazakh and Russian ethnical groups.
Materials and Methods: One hundred and forty patients with liver cirrhosis and 272 relatively healthy participants of both of nationalities were involved into research. АВ0, MNS, P1, CDE systems of erythrocytes of venous blood were investigated. For the comparison of the frequenc... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 80-89
PSYCHOTHERAPEUTIC REHABILITATION AND NORMALIZATION OF PSYCHOEMOTIONAL AND FUNCTIONAL CONDITION OF PATIENTS WITH PAIN SYNDROMES IN BRAIN ORGANIC LESIONS
Background. Psychoemotional violations impede adequate recovery of neurological function in patients with pain syndromes on a background of central nervous system, enhance their social and domestic roles, as well as substantially reduce the quality of life in patients.
Aim: to increase the efficiency of the rehabilitation of patients with pain syndromes on a background of organic defeat CNS.
Methods. The study has a prospective, comparative open character. The results of psychological rehabilitation were analyzed in 500 patients with stroke, head injury and suffering pain syndromes... Толығырақ
Aim: to increase the efficiency of the rehabilitation of patients with pain syndromes on a background of organic defeat CNS.
Methods. The study has a prospective, comparative open character. The results of psychological rehabilitation were analyzed in 500 patients with stroke, head injury and suffering pain syndromes... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 64-79
RNA SEQUENCING OF SQUAMOUS ESOPHAGEAL CANCER: FROM THE COLLECTION OF THE BIOMATERIAL UNTIL SEQUENCING ON HISEQ2000
The squamous esophageal cancer is a disease which is highly frequent in Kazakhstan, the frequency of the disease is 10,1:100 000. In the mortality structure esophageal cancer takes place among men the 5th place, among women the 9th place in the Republic of Kazakhstan. The molecular mechanisms which contribute to the initiation and progression of the cancer pathology are not investigated enough. Nevertheless, the lack of the sensitive and specific biomarkers for the diagnosis of the cancer diseases, underlines about the necessity of the additional research works to study about the development o...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 53-63
DEVELOPMENT OF HALOPLEX PANEL AND PREPARATION OF DNA LIBRARIES FOR TARGETED SEQUENCING OF CARDIAC ARRHYTHMIAS
Method of preparation of custom HaloPlex cardiogenetic panel (Agilent Technologies) and method of preparation of DNA libraries for targeted sequencing of 96 genes associated with cardiac arrhythmias were described in details in this article. SureDesign Online Design software (Agilent Technologies) was used to create the HaloPlex panel. Final design was developed for Illumina platform using Human Genome version 19, GRCh 37. 19958 amplicons were generated by the program, 99,46% of all target regions were covered successfully. DNA libraries were prepared for 48 samples using t...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 43-52
DETERMINATION OF GENETIC VARIANTS ASSOCIATED WITH HYPERTENSION, OBESITY AND DIABETES IN KAZAKH POPULATION TO STUDY INTERACTION OF GENETIC VARIANTS AND METABOLOME
In this work genetic variants associated with hypertension, obesity and diabetes were characterized, and genomic data of 60 samples were compared using Т-HOD (The Text-mined Hypertension, Obesity and Diabetes candidate gene database (T-HOD) international database.
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 30-42