EPIDEMIOLOGY, RESOURCE DISTRIBUTION, AND MANAGEMENT CHALLENGES OF CHRONIC HEART FAILURE IN KAZAKHSTAN: A NATIONAL RETROSPECTIVE ANALYSIS
2025 жыл | Шығарылым: 3 | Беттер: 7-15
PREVALENCE OF POLYMORPHISMS IN WARFARIN METABOLISM-RELATED GENES AMONG THE KAZAKH POPULATION
2025 жыл | Шығарылым: 3 | Беттер: 16-26
NEUROLOGICAL COMPLICATIONS IN EXTRACORPOREAL MEMBRANE OXYGENATION: RISK FACTORS FOR THE DEVELOPMENT OF ACUTE CEREBROVASCULAR EVENTS
2025 жыл | Шығарылым: 3 | Беттер: 27-35
THE EFFECT OF REPAGLINIDE AND METFORMIN ON EXTERNAL RESPIRATORY FUNCTION IN PATIENTS WITH DIABETES AND ISCHEMIC HEART DISEASE ASSOCIATED WITH OBESITY
2025 жыл | Шығарылым: 3 | Беттер: 36-41
RETROSPECTIVE ANALYSIS OF PATIENTS WITH OBLITERATING ATHEROSCLEROSIS OF THE LOWER EXTREMITY ARTERIES IN THE ABAI REGION OF THE REPUBLIC OF KAZAKHSTAN
2025 жыл | Шығарылым: 3 | Беттер: 42-52
ҚАНТ ДИАБЕТІНІҢ АСҚЫНУЛАРЫ БАР ANRIL(CDKN2B) ГЕНІНІҢ rs564398 ПОЛИМОРФИЗМІНІҢ АССОЦИАЦИЯСЫ 2 ТИПТІ ҚАНТ ДИАБЕТІ, АТАП АЙТҚАНДА ДИАБЕТТІК НЕЙРОПАТИЯНЫҢ ЖҮРЕК-ТАМЫР ТҮРІМЕН
2024 жыл | Шығарылым: 5 | Беттер: 55-61
МЕДИЦИНАЛЫҚ УНИВЕРСИТЕТТЕРДІҢ ПРОФЕССОРЛЫҚ-ОҚЫТУШЫЛЫҚ ҚҰРАМЫ АРАСЫНДА DEPRESSION ANXIETY STRESS SCALE (DASS-21) САУАЛНАМАСЫНЫҢ ҚАЗАҚША НҰСҚАСЫН ВАЛИДИЗАЦИЯЛАУ: ПИЛОТТЫҚ ЗЕРТТЕУ
2023 жыл | Шығарылым: 5 | Беттер: 262-269
АУРУХАНАЛАРДА ЖАҢА ТЕХНОЛОГИЯЛАРДЫ ЕНГІЗУ: МЕДИЦИНАЛЫҚ МАМАННЫҢ ХАБАРДАРЛЫҒЫ
2023 жыл | Шығарылым: 5 | Беттер: 135-143
ЖОҒАРЫ МЕДИЦИНАЛЫҚ БІЛІМ БЕРУДІҢ БЕЙІМДЕЛУ ОРТАСЫН ҚҰРУ ЖАҒДАЙЫНДА ПСИХОМЕТРИЯЛЫҚ ТЕСТІЛЕУДІҢ БОЛЖАМДЫҚ МӘНІ
2023 жыл | Шығарылым: 5 | Беттер: 253-261
DEVELOPMENT OF HALOPLEX PANEL AND PREPARATION OF DNA LIBRARIES FOR TARGETED SEQUENCING OF CARDIAC ARRHYTHMIAS
Method of preparation of custom HaloPlex cardiogenetic panel (Agilent Technologies) and method of preparation of DNA libraries for targeted sequencing of 96 genes associated with cardiac arrhythmias were described in details in this article. SureDesign Online Design software (Agilent Technologies) was used to create the HaloPlex panel. Final design was developed for Illumina platform using Human Genome version 19, GRCh 37. 19958 amplicons were generated by the program, 99,46% of all target regions were covered successfully. DNA libraries were prepared for 48 samples using t...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 43-52
DETERMINATION OF GENETIC VARIANTS ASSOCIATED WITH HYPERTENSION, OBESITY AND DIABETES IN KAZAKH POPULATION TO STUDY INTERACTION OF GENETIC VARIANTS AND METABOLOME
In this work genetic variants associated with hypertension, obesity and diabetes were characterized, and genomic data of 60 samples were compared using Т-HOD (The Text-mined Hypertension, Obesity and Diabetes candidate gene database (T-HOD) international database.
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 30-42
REPORT ABOUT THE CONFERENCE: THE INTERNATIONAL WОRLD HEALTH ORGANIZATION CONSULTATION ON NUTRITION AND PREGNANCY (27-28 June 2016, RIGA, LATVIA)
27-28 June 2016, Riga, Latvia hosted the International WHO consultation on nutrition and pregnancy, with participation of experts in the field of maternal and child health and the WHO Collaborating Centers from Poland, Latvia, Lithuania, Estonia, Italy, the UK, Kazakhstan, Tajikistan, Uzbekistan, Kyrgyzstan, Georgia, Armenia and Moldova. The key problems of women's health and nutrition, according to speakers from different countries are the following: the growth of overweight and obesity among women, excessive weight gain during pregnancy, low rates of exclusive breastfeeding in the first ...
Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 166-172
MODERN LAVAGE OF THE GASTROINTESTINAL TRACT FROM THE PERSPECTIVE OF THE QUALITY OF DIAGNOSIS AND TREATMENT IN ENDOSCOPIC, BARIATRIC SURGERY (LITERATURE REVIEW)
Introduction. The issue of quality lavage for the gastrointestinal tract before an abdominal surgery and endoscopic examination is of paramount significance, especially in patients with visceral obesity.
The aim of the study is to study historical aspects of intestinal cleansing, identify optimal ways to lavage and define its tolerability by patients.
Research methods. The review examines the effectiveness of different lavage techniques and patients’ preparation before surgeries and endoscopic examinations. The analysis of 77 sources relevant to the results of the study is also inc... Толығырақ
The aim of the study is to study historical aspects of intestinal cleansing, identify optimal ways to lavage and define its tolerability by patients.
Research methods. The review examines the effectiveness of different lavage techniques and patients’ preparation before surgeries and endoscopic examinations. The analysis of 77 sources relevant to the results of the study is also inc... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 145-165
HYPERHOMOCYSTEINEMIA AS A RISK FACTOR OF CARDIOVASCULAR DISEASES
Cardiovascular diseases are the leading cause of death. In this regard, the importance of the prevention problem increases, which is aimed at the identification and elimination of risk factors, which include elevated levels of homocysteine in the blood.
In recent years, actively studying the possibility of the use of B vitamins in vascular and neurodegenerative diseases. One of the main factors of hyperhomocysteinemia is the deficiency of vitamins B6, B12, B9 resulting from the features of the diet and impaired absorption. It was found that the use of preparations of B vitamins can reduc... Толығырақ
In recent years, actively studying the possibility of the use of B vitamins in vascular and neurodegenerative diseases. One of the main factors of hyperhomocysteinemia is the deficiency of vitamins B6, B12, B9 resulting from the features of the diet and impaired absorption. It was found that the use of preparations of B vitamins can reduc... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 129-144