ФОРМИРОВАНИЕ ОЧАГОВ Р53 СВЯЗАННОГО БЕЛКА 1 В ОПУХОЛЯХ ЩИТОВИДНОЙ ЖЕЛЕЗЫ: АКТИВАЦИЯ ГЕНЕТИЧЕСКОЙ НЕСТАБИЛЬНОСТИ В ТЕЧЕНИИ КАНЦЕРОГЕНЕЗА ЩИТОВИДНОЙ ЖЕЛЕЗЫ. ОБЗОР ЛИТЕРАТУРЫ
Введение: К настоящему времени достигнуты большие успехи в изучении молекулярно–клеточных механизмов канцерогенеза, установлении роли онкогенов и антионкогенов в развитии опухолей различной локализации, в том числе и РЩЖ. Подавляющее число доброкачественных и злокачественных опухолей щитовидной железы развивается из фолликулярного эпителия, которые имеют разную степень дифференцировки, разные морфогенетические и биохимические особенности, клиническое течение и прогноз.
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 25-37
ОРГАНИЗАЦИОННЫЕ ОСНОВЫ СКРИНИНГА КОЛОРЕКТАЛЬНОГО РАКА В МИРОВОЙ МЕДИЦИНСКОЙ ПРАКТИКЕ. ОБЗОР ЛИТЕРАТУРЫ
Актуальность. Рак ободочной и прямой кишки (колоректальный) является третьим по распространенности раком в мире. Он поддается скринингу, так как скрининговое исследование может быть осуществлено на предраковых, латентных, ранних и излечимых стадиях. При скрининге колоректального рака могут использоваться прямые или непрямые методы, применяемые произвольно или в структуре организованных программ. Большинство случаев колоректального рака диагностируется в возрасте старше 60 лет. Большинство программ скрининга относятся к лицам в возрасте 50-75 лет.
Цель обзора – Анализ подходов и р... Толығырақ
Цель обзора – Анализ подходов и р... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 13-24
MODERN TENDENCY IN TREATMENT OF PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY. LITERARY REVIEW
Relevance: Carrying out of intensive therapy at severe traumatic brain injury is a complex of measures aimed on saving of the brain tissues and maintaining its functions. To achieve this goal, it is necessary to do timely diagnostics and monitoring of critical parameters - intracranial pressure and cerebral perfusion pressure; pathogenetically based therapy and nutritional support for critically ill patients.
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 5-12
ЛЕЧЕНИЕ ПОПЕРЕЧНОГО ПЛОСКОСТОПИЯ С HALLUX VALGUS ПРИ I и II ТИПЕ РАСПЛАСТАННОСТИ СТОПЫ
Введение. Статическая деформация переднего отдела стопы составляет до 80% среди ортопедической патологии стопы у взрослых. Патология вызывает значительное нарушение биомеханики всей нижней конечности, сопровождаясь болью в переднем отделе стопы, затруднение в подборе и ношении обуви, значительно снижает трудоспособность и качество жизни пациента. В связи с этим разработка технологии лечения статической деформации переднего отдела стопы, предусматривающей устранение Halluxvalgus, metatarsusprimavarus и плантарную девиацию центральных лучей стопы остается не полностью решенной и актуальной п...
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2019 жыл | Шығарылым: 1 | Беттер: 80-90
АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ ШИГЕЛЛ НА СОВРЕМЕННОМ ЭТАПЕ
Введение. Одна из больших проблем практического здравоохранения на современном этапе – это рост антибиотикорезистентности шигелл к тем антибактериальным препаратам, которые широко сегодня используются в их лечении.
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 74-79
ASSESSMENT OF THE EFFECTIVENESS OF MEASURES TO PREVENT COMPLICATIONS OF SURGICAL TREATMENT IN PATIENTS WITH OCCLUSION OF THE AORTO-ILIAC SEGMENT
2025 жыл | Шығарылым: 5 | Беттер: 70-77
EVALUATION OF QUALITY OF LIFE IN PATIENTS AFTER SURGICAL TREATMENT OF POSTOPERATIVE VENTRAL HERNIAS
2025 жыл | Шығарылым: 5 | Беттер: 78-86
ACID–BASE BALANCE AND GAS EXCHANGE IN PATIENTS WITH DRUG-RESISTANT EPILEPSY DURING THE PERIOPERATIVE PERIOD: THE ROLE OF CLINICAL CHARACTERISTICS AND THERAPY
2025 жыл | Шығарылым: 5 | Беттер: 87-94
COMPARATIVE ASSESSMENT OF CANDIDA SPP. SUSCEPTIBILITY AND RESISTANCE TO ANTIFUNGAL AGENTS BY BIOLOGICAL MATERIAL TYPE
2025 жыл | Шығарылым: 5 | Беттер: 95-102
ASSESSMENT OF QUALITY OF LIFE IN HIV-INFECTED PATIENTS RECEIVING ANTIRETROVIRAL THERAPY USING THE STANDARDIZED SF-36 INSTRUMENT
2025 жыл | Шығарылым: 5 | Беттер: 103-111
INTRAABDOMINAL HYPERTENSION AND COMPARTMENT SYNDROME: REVIEW OF LITERATURE
The article presents a review of literature devoted to the intraabdominal hypertension and compartment syndrome. Based on the analysis of current books, publications, the views of domestic and foreign scientists in the article authors raises such controversial issues in this area now, as: value of intraabdominal pressure, methods and devices of measurement of intraabdominal pressure, theoretical and practical "border" between the intraabdominal hypertension and compartment syndrome, and also the reasons of development, classification, pathophysiology, clinic, treatment and prevention...
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2015 жыл | Шығарылым: 1 | Беттер: 22-32
SURGICAL TREATMENT OF INTRACEREBRAL HEMORRHAGE IN PREGNANT WOMEN
The emergence of urgent neurosurgical conditions in pregnant women is a complex multidisciplinary problem which decision requires participation of experts of several adjacent specialties.
Objective: to show the possibility of surgical treatment of non-traumatic intracerebral hematomas (NICH) in case of women in late terms of pregnancy.
Research methods: there were two women in the late terms of pregnancy with NISG in office of neurosurgery of the Medical center of the State medical university of the Semey city were operated. One of these supervision is given. Th... Толығырақ
Objective: to show the possibility of surgical treatment of non-traumatic intracerebral hematomas (NICH) in case of women in late terms of pregnancy.
Research methods: there were two women in the late terms of pregnancy with NISG in office of neurosurgery of the Medical center of the State medical university of the Semey city were operated. One of these supervision is given. Th... Толығырақ
2015 жыл | Шығарылым: 1 | Беттер: 77-80
CONDITION OF COAGULATION HEMOSTASIS AMONG WOMEN, WHO ARE IN THE RISK GROUP BY POSTPARTUM HAEMORRHAGE DEPENDING ON CHILDBIRTHS PARITY
Background: Obstetric haemorrhage is the important issue of obstetrics and one of the major causes of maternal mortality and morbidity in the world. Multiparous women take up a large proportion among dead women. More than 2/3 of blood loss, including threatening the mother’s life, is associated with disorders of hemostasis.
The aim: to evaluate the coagulation system in women with risk factors for postpartum haemorrhage depending on childbirths parity.
Methods: 126 pregnant women were examined, i.e. 96 pregnant women of haemorrhage risk group and 30 pregnant women with physiologic ... Толығырақ
The aim: to evaluate the coagulation system in women with risk factors for postpartum haemorrhage depending on childbirths parity.
Methods: 126 pregnant women were examined, i.e. 96 pregnant women of haemorrhage risk group and 30 pregnant women with physiologic ... Толығырақ
2015 жыл | Шығарылым: 1 | Беттер: 60-69
FUNCTION SINGULARITIES OF THE THYROID GLAND DURING THE PREGNANCY: REVIEW OF LITERATURE
This review contains discusses of functional properties of the thyroid gland during the physiological pregnancy, particularly during in its different periods. Influence of iodine insufficiency and radioactive effects on the functional status of the pregnant women’s thyroid gland. Influence of the pathology of the thyroid gland on pregnancy, a fetus and a pregnant woman. Also, methods of correction of various pathological changes of functions of the thyroid gland during the gestation are discussed, as they can lead tohabitual miscarriage and to the pathology of the newborn. Preventive measures ...
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2015 жыл | Шығарылым: 1 | Беттер: 13-21
THE NEED FOR IMPROVEMENT OF THE QUALITY OF KAZAKHSTANI PUBLICATIONS FOR SUCCESSFUL INTEGRATION IN THE INTERNATIONAL RESEARCH COMMUNITY
This is an introductory article which opens a series of publications about basic principles of research design in health sciences and statistical analysis of biomedical data. In this paper we present a non-systematic review of literature assessing scientific quality of publications in Kazakhstan and other countries justifying the need for improvement of quality of Kazakhstani research papers, which is a pre-requisite of successful integration in the international biomedical research community. The series will cover cross-sectional, cohort, cross-sectional, ecological and experimental studies, ...
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2015 жыл | Шығарылым: 1 | Беттер: 5-12