ФОРМИРОВАНИЕ ОЧАГОВ Р53 СВЯЗАННОГО БЕЛКА 1 В ОПУХОЛЯХ ЩИТОВИДНОЙ ЖЕЛЕЗЫ: АКТИВАЦИЯ ГЕНЕТИЧЕСКОЙ НЕСТАБИЛЬНОСТИ В ТЕЧЕНИИ КАНЦЕРОГЕНЕЗА ЩИТОВИДНОЙ ЖЕЛЕЗЫ. ОБЗОР ЛИТЕРАТУРЫ
Введение: К настоящему времени достигнуты большие успехи в изучении молекулярно–клеточных механизмов канцерогенеза, установлении роли онкогенов и антионкогенов в развитии опухолей различной локализации, в том числе и РЩЖ. Подавляющее число доброкачественных и злокачественных опухолей щитовидной железы развивается из фолликулярного эпителия, которые имеют разную степень дифференцировки, разные морфогенетические и биохимические особенности, клиническое течение и прогноз.
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 25-37
ОРГАНИЗАЦИОННЫЕ ОСНОВЫ СКРИНИНГА КОЛОРЕКТАЛЬНОГО РАКА В МИРОВОЙ МЕДИЦИНСКОЙ ПРАКТИКЕ. ОБЗОР ЛИТЕРАТУРЫ
Актуальность. Рак ободочной и прямой кишки (колоректальный) является третьим по распространенности раком в мире. Он поддается скринингу, так как скрининговое исследование может быть осуществлено на предраковых, латентных, ранних и излечимых стадиях. При скрининге колоректального рака могут использоваться прямые или непрямые методы, применяемые произвольно или в структуре организованных программ. Большинство случаев колоректального рака диагностируется в возрасте старше 60 лет. Большинство программ скрининга относятся к лицам в возрасте 50-75 лет.
Цель обзора – Анализ подходов и р... Толығырақ
Цель обзора – Анализ подходов и р... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 13-24
MODERN TENDENCY IN TREATMENT OF PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY. LITERARY REVIEW
Relevance: Carrying out of intensive therapy at severe traumatic brain injury is a complex of measures aimed on saving of the brain tissues and maintaining its functions. To achieve this goal, it is necessary to do timely diagnostics and monitoring of critical parameters - intracranial pressure and cerebral perfusion pressure; pathogenetically based therapy and nutritional support for critically ill patients.
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 5-12
ЛЕЧЕНИЕ ПОПЕРЕЧНОГО ПЛОСКОСТОПИЯ С HALLUX VALGUS ПРИ I и II ТИПЕ РАСПЛАСТАННОСТИ СТОПЫ
Введение. Статическая деформация переднего отдела стопы составляет до 80% среди ортопедической патологии стопы у взрослых. Патология вызывает значительное нарушение биомеханики всей нижней конечности, сопровождаясь болью в переднем отделе стопы, затруднение в подборе и ношении обуви, значительно снижает трудоспособность и качество жизни пациента. В связи с этим разработка технологии лечения статической деформации переднего отдела стопы, предусматривающей устранение Halluxvalgus, metatarsusprimavarus и плантарную девиацию центральных лучей стопы остается не полностью решенной и актуальной п...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 80-90
АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ ШИГЕЛЛ НА СОВРЕМЕННОМ ЭТАПЕ
Введение. Одна из больших проблем практического здравоохранения на современном этапе – это рост антибиотикорезистентности шигелл к тем антибактериальным препаратам, которые широко сегодня используются в их лечении.
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 74-79
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
GENETIC VARIANTS IN LIPID-ASSOCIATED GENES IN THE KAZAKHSTANI COHORT WITH ATHEROSCLEROSIS AND HYPERTRIGLYCERIDEMIA
2025 жыл | Шығарылым: 5 | Беттер: 7-15
CLONAL HEMATOPOIESIS WITH INDETERMINATE POTENTIAL IN TET2 AND DNMT3A AMONG KAZAKHSTANI INDIVIDUALS WITH ATHEROSCLEROTIC DISEASE
2025 жыл | Шығарылым: 5 | Беттер: 16-23
USING WORLD HEALTH ORGANIZATION RECOMMENDATIONS CONSUMPTION ASSESSMENT OF THE ANTIBIOTICS PURCHASED A SINGLE DISTRIBUTION WITHIN THE GUARANTEED VOLUME OF FREE MEDICAL CARE FOR THE PERIOD 2012-2016
Background. One of the key principles of rational use of antibiotics is high quality and reasonable assessment of their consumption. In this paper we used data on medicines purchased by a Single distributor within the guaranteed volume of free medical care for the period 2012 – 2016 гг, submitted by the Committee of Pharmacy of the Health Ministry of the Republic of Kazakhstan (CP HM RK).
Objectives. Evaluation of the consumption of antiinfectives for systemic use, section J01 - antiinfectives for systemic use purchased under the guaranteed volume of free medical care by a... Толығырақ
Objectives. Evaluation of the consumption of antiinfectives for systemic use, section J01 - antiinfectives for systemic use purchased under the guaranteed volume of free medical care by a... Толығырақ
2017 жыл | Шығарылым: 2 | Беттер: 34-47
UNIVARIATE REGRESSION ANALYSIS USING STATISTICA AND SPSS SOFTWARE
In this paper we present basic concepts of simple linear regression analysis using Statistica and SPSS software. Special emphasis is given to interpretation of the outputs provided by software packages. The article provides general knowledge and practical advices regarding the use of simpla logistic regression in biomedical studies, but it does not substitute specialized literature on biostatistics.
Толығырақ
2017 жыл | Шығарылым: 2 | Беттер: 5-33
FOREIGN AND NATIVE EXPERIENCE OF CARE AGAINST TUBERCULOSIS FOR HIV – INFECTED PATIENTS. Review.
Introduction. Co - infection of tuberculosis / human immunodeficiency virus (TB/HIV) is not only one of the most common combinations of dual infection among people living with HIV, but also the most dangerous for the patient and for society as a whole.
The aim of our review was to study the organization of TB care to patients with HIV infection in Kazakhstan and foreign countries.
Research methods. The study included full-text publications in English and Russian languages, which were devoted to the study of the organization of TB care to people livi... Толығырақ
The aim of our review was to study the organization of TB care to patients with HIV infection in Kazakhstan and foreign countries.
Research methods. The study included full-text publications in English and Russian languages, which were devoted to the study of the organization of TB care to people livi... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 166-179
AWARENESS AND TRUST ON VACCINATION OF THE WOMEN LIVING IN EAST KAZAKHSTAN REGION ON THE RESULTS OF THE SURVEY
Background: Questions of trust in vaccination becomes a relevant view of the increase cases of refusal of vaccination in the last time, and the knowledge about the sources of information on vaccination definitely can impact further to health education work in this direction.
Objectives: To study the sources of information about vaccination and the credibility of these sources among the population of East Kazakhstan Regon.
Methods: Questionnaire is designed for parents with children under 3 years living in Semey and EKR. The questionnaire included 36 blocks of question... Толығырақ
Objectives: To study the sources of information about vaccination and the credibility of these sources among the population of East Kazakhstan Regon.
Methods: Questionnaire is designed for parents with children under 3 years living in Semey and EKR. The questionnaire included 36 blocks of question... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 156-165
SCREENING OF DIABETIC RETINOPATHY IN A POPULATION OF PAVLODAR REGION
Introduction: diabetic retinopathy is a specific diabetes-induced vascular complication associated with the stable retinal malfunctioning. This is the commonest cause of blindness in the labour-active part of population in developed nations being responsible for 80-90% of all diabetes-related ocular disability.
Aim: to screen the population of patients with diabetes followed by the State Diabetes Register in order to elucidate the prevalence and the structure of diabetic retinopathy.
Materials and methods: this was a cross-sectional study. Overall, we examined 310... Толығырақ
Aim: to screen the population of patients with diabetes followed by the State Diabetes Register in order to elucidate the prevalence and the structure of diabetic retinopathy.
Materials and methods: this was a cross-sectional study. Overall, we examined 310... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 146-155