ВЛИЯНИЕ ОТДАЛЕННЫХ ПОСЛЕДСТВИЙ ОСТРОГО ГАММА-ИЗЛУЧЕНИЯ И ЭМОЦИОНАЛЬНОГО СТРЕССА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ КОСТНОГО МОЗГА И ТИМУСА
В раннем периоде общего адаптационного синдрома снижается масса тимуса, повышается количество лимфо-идных клеток, в последующей стадии в тимусе возрастает масса и нормализуется число лимфоидных клеток. Во всех фазах адаптационного синдрома в костном мозге происходит повышение лимфоидных клеток.
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 62-65
ОТДАЛЕННЫЕ ЭФФЕКТЫ РАЗНОЙ ДОЗЫ ГАММА-ИЗЛУЧЕНИЯ НА ЛИМФОИДНЫЕ ОРГАНЫ ИММУНОГЕНЕЗА
В отдаленном периоде после сублетального и фракционированного действия гамма-излучения в тимусе и лим-фатических узлах тонкого кишечника снижены количества лимфоидных клеток. В тимусе и селезенке определяется атрофия, в лимфатических узлах тонкого кишечника - сниженный лимфоидный индекс и лимфоидных клеток.
В отдаленном периоде после воздействия малой дозы гамма-излучения отмечается атрофия тимуса и перерас-пределение лимфоидных клеток из тимуса и лимфатических узлов тонкого кишечника в костный мозг и селезенку.
Толығырақ
В отдаленном периоде после воздействия малой дозы гамма-излучения отмечается атрофия тимуса и перерас-пределение лимфоидных клеток из тимуса и лимфатических узлов тонкого кишечника в костный мозг и селезенку.
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 49-53
DENTAL STATUS OF PATIENTS DURING THE SUPPORTIVE CARE AT ANTINEOPLASTIC CHEMOTHERAPY FOR BREAST CANCER
Two groups were studied in a comparative aspect – 98 women with breast cancer during the courses of adjuvant chemo-therapy: the first was comprised of 26 patients who used their conventional means for oral hygiene; the second included 72 patients, who received the complex of therapeutic and preventive measures of supportive care. Dental toxicity was observed in 84.6-96.2 %, and has grown with the increase of the cycles of chemotherapy, reaching a maximum value on the V cycle of treatment. It is shown that the application of the developed complex significantly reduces the manifestations of ...
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 35-39
ДАННЫЕ СКРИНИНГА ПАТОЛОГИИ ЩИТОВИДНОЙ ЖЕЛЕЗЫ У ЖИТЕЛЕЙ РАЙОНОВ, ПОДВЕРГШИХСЯ РАДИАЦИОННОМУ ОБЛУЧЕНИЮ
В статье приведены данные, полученные в результате скрининга населения районов, подвергшихся радиационному облучению. Целью исследования было выявление частоты и особенностей патологии щитовидной железы у жителей районов Павлодарской и Восточно-Казахстанской областей, подвергшиеся радиационному облучению. Обследовано 1783 человека. Диффузный эутиреоидный зоб диагностирован в 32,97% случаев, колло-идно-узловой зоб у 13,60% обследованных, аутоиммуный тиреоидит у 52,96%, в 2,4% случаев наблюдался много-узловой зоб. Анализ функционального состояния щитовидной железы пока...
Толығырақ
2014 жыл | Шығарылым: 3 | Беттер: 22-25
МОДЕЛИРОВАНИЕ САХАРНОГО ДИАБЕТА 2 ТИПА ДЛЯ ИЗУЧЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ С АНТИДИАБЕТИЧЕСКОЙ АКТИВНОСТЬЮ
Учитывая неуклонно возрастающее во всем мире число больных сахарным диабетом 2 типа, актуальной проблемой современной фармакологии продолжает оставаться разработка антидиабетических препаратов, обладающих высокой терапевтической активностью и имеющих более совершенный профиль безопасности. В связи с этим важное значение имеет моделирование сахарного диабета, позволяющее достоверно выявлять наличие той или иной фармакологической активности или новых деталей в механизме действия лекарственных средств. Модели сахарного диабета могут быть получены на различных видах животных ...
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 4-8
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
ASSESSMENT OF THE PROBABILITY OF DEVELOPING CARDIORENAL SYNDROME TYPE 2 DEPENDING ON POTENTIAL BIOMARKERS IN PEDIATRIC PATIENTS
2025 жыл | Шығарылым: 6 | Беттер: 21-29
MORPHO-GENETIC VARIABILITY IN MYOCARDIAL TISSUE AFTER SEPTAL MYECTOMY IN PATIENTS WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: A FOUR-CASE SERIES STUDY
2025 жыл | Шығарылым: 6 | Беттер: 30-37
CLINICAL EFFICACY OF SELECTIVE PLASMA FILTRATION (EVACLIO) IN CARDIOVASCULAR COMPLICATIONS: A CASE SERIES FROM THE HEART CENTER KAZAKHSTAN
2025 жыл | Шығарылым: 6 | Беттер: 38-46
METABOLIC EFFECTS OF COMBINED INTEGRATION OF ADENOSINE AND ADENOSINE MONOPHOSPHAT IN HYPERADENALEMEMIA
Introduction. It is known that adenosine as a metabolite of adenosune monophosphate (AMP) has a variety of functional and metabolic effects aimed at maintaining homeostasis. Adenosine plays a particularly important role in the adaptation of the myocardium to ischemia and hypoxia. By exerting an antiarrhythmic effect on the heart, adenosine slows the atrioventricular conduction induced by catecholamines.
Purpose of the study. To study the effects of the combined effect of the adenosine + AMP complex on the immune status, on the activity of antioxidant protection enzymes... Толығырақ
Purpose of the study. To study the effects of the combined effect of the adenosine + AMP complex on the immune status, on the activity of antioxidant protection enzymes... Толығырақ
2017 жыл | Шығарылым: 2 | Беттер: 92-104
IMMUNE STATUS, ANTIOXIDANT PROTECTION SYSTEM AND ENZYMES OF METABOLISM OF PURINE NUCLEOTIDES IN SYMPATHETIC HYPERACTIVATION
Introduction. It is known that activation of the sympathoadrenal system aggravates the course of coronary heart disease. And elevated levels of catecholamines are a risk factor for the development of repeated myocardial infarction and sudden death.
Purpose of the study. With hyperadrenalinemia caused by the administration of adrenaline to animals at a dose of 4 mg / kg 60 minutes before the study, to study the status of the immune status, the parameters of the antioxidant defense system and the enzymes of the purine nucleotide metabolism.
Material and methods. Study d... Толығырақ
Purpose of the study. With hyperadrenalinemia caused by the administration of adrenaline to animals at a dose of 4 mg / kg 60 minutes before the study, to study the status of the immune status, the parameters of the antioxidant defense system and the enzymes of the purine nucleotide metabolism.
Material and methods. Study d... Толығырақ
2017 жыл | Шығарылым: 2 | Беттер: 80-91
OSTEODENSITOMETRY PARAMETERS ADOLESCENTS AGED 12-18 YEARS IN AKTOBE
Introduction. Conducted in the last decade, epidemiological studies have convincingly demonstrated that the OP problem originates in childhood in adult patients. It is known, that the formation of bones occurs in the early years of life, their mass (mineral density) reaches a maximum by 18-20 years. Violation of the processes of bone formation in a child under the influence of so-called pre-morbid conditions or chronic diseases leads to the formation of a decrease in bone strength already in childhood and, as a consequence, an increased risk of osteoporosis and bone fractures in the fu...
Толығырақ
2017 жыл | Шығарылым: 2 | Беттер: 68-79
EFFICIENCY OF ALTERNATIVE TREATMENT OF NODULAR FORMS OF THYROID GLAND
Introduction. An analysis of the medical literature on minimally invasive treatment of benign tumors of the thyroid gland showed a lack of consensus among endocrinologists and surgeons for the treatment of cystic and solid thyroid nodules.
The aim of the study was to research the experience of using percutaneous ethanol injection therapy (PEI) in patients with benign thyroid neoplasms.
Materials and methods. We conducted a prospective cohort study. The study period was on average 10 ± 1.2 years for each participant. The work was started between May 1993 and Ju... Толығырақ
The aim of the study was to research the experience of using percutaneous ethanol injection therapy (PEI) in patients with benign thyroid neoplasms.
Materials and methods. We conducted a prospective cohort study. The study period was on average 10 ± 1.2 years for each participant. The work was started between May 1993 and Ju... Толығырақ
2017 жыл | Шығарылым: 2 | Беттер: 59-67
ASSESSMENT OF SUICIDAL RISK IN THE FIRST-YEAR STUDENTS AT A MEDICAL UNIVERSITY (PANEL STUDY)
Introduction: Kazakhstan continues to be one of the countries, where the percent of suicides is considerably high. The problem of suicides among younger people is especially relevant. Exposure to psychological stresses, including those connected with a necessity of adaptation to new academic conditions, is one of the suicidal risks factors.
Aim of the study: dynamic assessment of the suicidal risk in the first-year students of a medical university, applying the process of the adaptation toward the academic conditions.
Methods: the two-waved panel assessment of suicida... Толығырақ
Aim of the study: dynamic assessment of the suicidal risk in the first-year students of a medical university, applying the process of the adaptation toward the academic conditions.
Methods: the two-waved panel assessment of suicida... Толығырақ
2017 жыл | Шығарылым: 2 | Беттер: 48-58