Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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МИОКАРД ИНФАРКТІМЕН БІРІККЕН ЦЕРЕБРОВАСКУЛЯРЛЫ ПАТОЛОГИЯСЫ БАР НАУҚАСТАРДАҒЫ HLA АНТИГЕНДЕРІНІҢ БӨЛІНУІ
Всего обследовано 25 больных с инфарктом миокарда сочетанной с цереброваскулярной патологией. Кон-трольную группу составили доноры здоровые лица 442 человек. Типирование антигенов гистосовместимости HLA I класса проводились в стандартном двухступенчатом микролимфоцитоксическом тесте. Иммуногенетическими маркерами повышенного риска заболеваемости инфаркта миокарда при сочетании цереброваскулярной патологией у казахов являются антигены HLA А1, А2, А9, В5, В7, В12, В35, В40 и гаплотипы А1/В12, А2/В12, А9/В12; у русских HLA А10, В5, В7, В17, В40; фенотип В7/В8 и гаплотипы А10/В5, А10/В7. Протектив...
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 23-26

Влияние радиационных и нерадиационных факторов риска на формирование заболева-ний системы кровообращения и методы их профилактики с позиции доказательной меди-цины
В статье представлен литературный обзор по проблеме изучения радиационных и нерадиационных факторов риска болезней системы кровообращения. Проведен анализ информации из баз данных по доказательной медицине по профилактическим и реабилитационным мероприятиям, включающим длительный и постоянный мониторинг путем проведения скрининговых обследований на местах
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 20-23

ДОНОЗОЛОГИЧЕСКАЯ ДИАГНОСТИКА И ПРОФИЛАКТИКА БОЛЕЗНЕЙ СИСТЕМЫ КРОВООБРАЩЕНИЯ У ЛИЦ, ПОДВЕРГАВШИХСЯ ВОЗДЕЙСТВИЮ РАДИАЦИОННОГО ФАКТОРА, НА ОСНОВЕ ИЗУЧЕНИЯ ГЕННОГО ПОЛИМОРФИЗМА
В статье представлены принципы донозологической диагностики социально значимых болезней системы кровообращения на основе определения полиморфизма генов-кандидатов, определяющих уровень артериального давления, обмен гомоцистеина и метаболизм липидов. Исследование позволило установить высокую корреляци-онную связь гетерозиготных нарушений в отношении гена-кандидата AGT, предполагающую высокую степень наследования  сосудистой патологии экспонированных радиацией родителей их потомками. Результаты ис-следований свидетельствуют о необходимости совершенствования системы длительного монитори...
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 18-20

К ПРОБЛЕМЕ ОРГАНИЗАЦИИ САМОСТОЯТЕЛЬНОЙ РАБОТЫ СТУДЕНТОВ
В статье рассматривается проблема организации самостоятельной работы студентов. Oриентация  на СРС при хорошо организованном и научно обоснованном методическом обеспечении повышает качественные пока-затели образовательного процесса, дает совершенно новые возможности.
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 15-17

CONGENITAL HEART DISEASES AND CONNECTIVE TISSUE DYSPLASIA CHILDREN OF SEMEY, THE DETERMINATION THE FREQUENCY
Introduction. The community of pathogenetic mechanisms of congenital heart diseases and connective tissue dysplasia connective tissue dysplasia defines increase in risk of their combinations. At the same time perhaps essential deterioration in the forecast of a current and conditions for correction of connective tissue dysplasia. So far poorly studied are an actual frequency and structure of combinations of these pathological states in population. Research objective – to determine the frequency of signs connective tissue dysplasia in children with connective tissue dysplasia are living in S...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 145-152

FACTORS OF ADDICTIVE PREDISPOSITION AMONG FIRST-YEAR STUDENTS OF SEMEY STATE MEDICAL UNIVERSITY
Introduction: Training in a medical university is associated with a tense adaptation, which leads to a change in the mental status of students. This may result in vulnerability to addictions and the possible development of dependent behavior. The aim of the study was to determine the prevalence of the addiction risk in students of the Semey State Medical University of (SSMU), as well as in the context of interrelated socio-psychological factors. Materials and methods: A one-stage cross-sectional evaluation was carried out using a questionnaire of 643 first-year students of the Semey State Me...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 135-144

PREVALENCE AND SEVERITY OF SOMATIC DISTRESS AND FATIGUE AMONG RESIDENTS OF EAST KAZAKHSTAN REGION EXPOSED TO RADIATION DUE TO THE ACTIVITY OF THE SEMIPALATINSK NUCLEAR TEST SITE
Background: since Kazakhstan belongs to the range of industrialized world nations, most of its territory is affected by anthropogenic and man-induced risk factors, which contribute to the development of unfavorable ecological situation that has negative impact on the population health. Nuclear weapons tests at the Semipalatinsk nuclear test site have caused significant adverse changes in the habitat of hundreds of thousands of people who are now forced to live and conduct economic activities in territories contaminated with radionuclides. Studying the long-term effects of small radiation doses...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 125-134

PREVALENCE AND SEVERITY OF DEPRESSION AND ANXIETY AMONG RESIDENTS OF EAST KAZAKHSTAN REGION DEPENDING ON RADIATION EXPOSURE DUE TO THE ACTIVITY OF THE SEMIPALATINSK NUCLEAR TEST SITE
Background: studying the influence of environmental factors on mental health of the population is a widespread approach among modern researchers, which allows us to characterize the state of mental health both at individual and population levels. Assessment of mental distress is a necessary measure for the development of primary and secondary prevention programs on mental disorders. Despite the closure of the Semipalatinsk Nuclear Test Site (SNTS) in 1989, many social, demographic and economic issues remained unresolved. There is an aggravation of psychological tension among residents of the t...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 115-124

ASSESSMENT OF BIOCHEMICAL INDICATORS CHARACTERIZING THE HEALTH STATUS OF THE POPULATION OF THE EAST KAZAKHSTAN REGION EXPOSED TO RADIATION DUE TO NUCLEAR WEAPONS TESTS
Introduction: In 2017, the scientific program "Development of scientific and methodological foundations for minimizing environmental burden, medical provision, social protection and health improvement of the population of ecologically unfavorable territories of the Republic of Kazakhstan" was started in the SMU. In the framework of the program we studied the state of health and nonspecific resistance in the population of the East Kazakhstan region exposed to radiation. Aim: assessment of biochemical indicators characterizing the health status of the studied population Methods: The sample si...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 105-114