ИННОВАЦИОННАЯ ТЕРАПИЯ РЕВМАТИЧЕСКИХ ЗАБОЛЕВАНИЙ
В статье по результатам международного опыта и собственных исследований представлены современные направления в лечении аутоиммунных ревматических заболеваний с использованием генно-инженерных биологических антицитокиновых препаратов, ингибиторов внутриклеточных ферментов – киназ для лечения по принципу «treat to target». Данные этой статьи будут полезны или интересны для интернов, резидентов и врачей – ревматологов, а также для преподавателей медицинских университетов
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2019 жыл | Шығарылым: 1 | Беттер: 99-104
АНАЛИЗ РЕЗУЛЬТАТОВ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ ГИПОСПАДИИ У ДЕТЕЙ ЗА 2010 – 2015 ГОДЫ
Введение. Для лечения гипоспадии в последние десятилетия стали широко применять различные методы хирургической коррекции. Несмотря на это встречаются различные виды осложнений как в раннем послеоперационном, так и в отдаленном периодах.
Цель. Провести анализ результатов хирургического лечения гипоспадии одномоментными и этапными методами уретропластики.
Материалы и методы. Проведено одномоментное поперечное исследование результатов хирургического лечения гипоспадии у мальчиков в возрасте от трех месяцев до 17 лет, которые находились на стационарном лечении в «Национальном Научном Ц... Толығырақ
Цель. Провести анализ результатов хирургического лечения гипоспадии одномоментными и этапными методами уретропластики.
Материалы и методы. Проведено одномоментное поперечное исследование результатов хирургического лечения гипоспадии у мальчиков в возрасте от трех месяцев до 17 лет, которые находились на стационарном лечении в «Национальном Научном Ц... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 91-98
ИСТОРИЯ И ПЕРСПЕКТИВЫ РАЗВИТИЯ МАГНИТНО-РЕЗОНАНСНОЙ ТОМОГРАФИИ
Магнитно-резонансная томография - метод исследования, основанный на получении изображения тканей и органов при помощи электромагнитных волн. К достоинствам магнитно-резонансной томографии относятся высокая контрастность мягкотканых структур, связочного аппарата, тканей головного и спинного мозга, отсутствие лучевой нагрузки. Магнитно-резонансная томография позволяет проводить исследование в любых плоскостях с учетом анатомических особенностей тела пациента, а при необходимости – получать трехмерные изображения для точной оценки взаиморасположения различных органов и тканей. Начиная с конца 90-...
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2018 жыл | Шығарылым: 6 | Беттер: 169-175
JOINT DEVELOPMENT MEDICAL UNIVERSITY CITY OF SEMEY AND THREE PREFECTURES OF JAPAN THAT BASED ON OUR HISTORY OF INTERNATIONAL EXCHANGE
In the current era of globalization, universities are working to conclude agreements on international exchanges. Such agreements are concluded as a result of support from various quarters and departments within the university. International exchanges between Kazakhstan and Japan have progressed over the past few years. Semey State Medical University and Kochi University concluded an agreement on academic cooperation and student exchanges in 2018. This agreement follows on the heels of similar agreements concluded between Semey State Medical University and Hiroshima and Shimane universities.
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2018 жыл | Шығарылым: 6 | Беттер: 163-168
НЕВРОЛОГИЧЕСКИЕ НАРУШЕНИЯ ПРИ ВИЧ-ИНФЕКЦИИ. КЛИНИЧЕСКИЙ СЛУЧАЙ.
Введение. В современном обществе вирус иммунодефицита человека обладает статусом «глобальной социальной проблемы». В Казахстане благодаря комплексу целенаправленных профилактических мероприятий ВИЧ-инфекция удерживается на концентрированной стадии, то есть распространение происходит преимущественно среди уязвимых групп. В динамике снижается частота парентерального пути заражения, растет удельный вес полового пути, наблюдается увеличение случаев ВИЧ-инфекции среди лиц более старшей возрастной группы и разнообразней становятся клинические проявления.
Цель исследования. Анализ клинического ... Толығырақ
Цель исследования. Анализ клинического ... Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 157-162
РАДИАЦИЯЛЫҚ ӘСЕРГЕ ТАП БОЛҒАН АДАМДАРДЫҢ ІШІНДЕ, ҚАН АЙНАЛЫМ ЖҮЙЕСІ АУРУЛАРЫН БОЛЖАУ ТӘСІЛДЕРІ, ЕРТЕ ДИАГНОСТИКАЛАУ, ЕМДЕУ ЖӘНЕ ПРОФИЛАКТИКА
2013 жыл | Шығарылым: 2 | Беттер: 22-24
MORTALITY FROM CARDIOVASCULAR DISEASES IN THE POPULATION OF KAZAKHSTAN EXPOSED TO RADIATION
2013 жыл | Шығарылым: 2 | Беттер: 16-21
ӨКПЕНІҢ СОЗЫЛМАЛЫ ОБСТРУКТИВТІ АУРУЫНЫҢ ЕМДЕУІН ЖӘНЕ АУРУДЫҢ АҚЫРЫН БОЛЖАМДАУ, АУЫРЛЫҒЫН БАҒАЛАУ ЖӘНЕ АНЫҚТАУ ЖОЛДАРЫНЫҢ ҚИЫНДЫҚТАРЫ
2013 жыл | Шығарылым: 2 | Беттер: 13-15
ӨКПЕНІҢ СОЗЫЛМАЛЫ ОБСТРУКТИВТІ АУРУЫ КЕЗІНДЕГІ БІРІККЕН ЕМГЕ ЗАМАНАУИ КӨЗҚАРАС
2013 жыл | Шығарылым: 2 | Беттер: 6-12
МЕДИЦИНАЛЫҚ ЖОҒАРҒЫ ОҚУ ОРЫНДАРЫНДА МАМАНДЫҚТАР БОЙЫНША МӘТІНДЕР АРҚЫЛЫ КӘСІБИ ТІЛДЕСУГЕ ОҚЫТУ
2013 жыл | Шығарылым: 1 | Беттер: 10-11
PSYCHOTHERAPEUTIC REHABILITATION AND NORMALIZATION OF PSYCHOEMOTIONAL AND FUNCTIONAL CONDITION OF PATIENTS WITH PAIN SYNDROMES IN BRAIN ORGANIC LESIONS
Background. Psychoemotional violations impede adequate recovery of neurological function in patients with pain syndromes on a background of central nervous system, enhance their social and domestic roles, as well as substantially reduce the quality of life in patients.
Aim: to increase the efficiency of the rehabilitation of patients with pain syndromes on a background of organic defeat CNS.
Methods. The study has a prospective, comparative open character. The results of psychological rehabilitation were analyzed in 500 patients with stroke, head injury and suffering pain syndromes... Толығырақ
Aim: to increase the efficiency of the rehabilitation of patients with pain syndromes on a background of organic defeat CNS.
Methods. The study has a prospective, comparative open character. The results of psychological rehabilitation were analyzed in 500 patients with stroke, head injury and suffering pain syndromes... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 64-79
RNA SEQUENCING OF SQUAMOUS ESOPHAGEAL CANCER: FROM THE COLLECTION OF THE BIOMATERIAL UNTIL SEQUENCING ON HISEQ2000
The squamous esophageal cancer is a disease which is highly frequent in Kazakhstan, the frequency of the disease is 10,1:100 000. In the mortality structure esophageal cancer takes place among men the 5th place, among women the 9th place in the Republic of Kazakhstan. The molecular mechanisms which contribute to the initiation and progression of the cancer pathology are not investigated enough. Nevertheless, the lack of the sensitive and specific biomarkers for the diagnosis of the cancer diseases, underlines about the necessity of the additional research works to study about the development o...
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2016 жыл | Шығарылым: 5 | Беттер: 53-63
DEVELOPMENT OF HALOPLEX PANEL AND PREPARATION OF DNA LIBRARIES FOR TARGETED SEQUENCING OF CARDIAC ARRHYTHMIAS
Method of preparation of custom HaloPlex cardiogenetic panel (Agilent Technologies) and method of preparation of DNA libraries for targeted sequencing of 96 genes associated with cardiac arrhythmias were described in details in this article. SureDesign Online Design software (Agilent Technologies) was used to create the HaloPlex panel. Final design was developed for Illumina platform using Human Genome version 19, GRCh 37. 19958 amplicons were generated by the program, 99,46% of all target regions were covered successfully. DNA libraries were prepared for 48 samples using t...
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2016 жыл | Шығарылым: 5 | Беттер: 43-52
DETERMINATION OF GENETIC VARIANTS ASSOCIATED WITH HYPERTENSION, OBESITY AND DIABETES IN KAZAKH POPULATION TO STUDY INTERACTION OF GENETIC VARIANTS AND METABOLOME
In this work genetic variants associated with hypertension, obesity and diabetes were characterized, and genomic data of 60 samples were compared using Т-HOD (The Text-mined Hypertension, Obesity and Diabetes candidate gene database (T-HOD) international database.
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 30-42
REPORT ABOUT THE CONFERENCE: THE INTERNATIONAL WОRLD HEALTH ORGANIZATION CONSULTATION ON NUTRITION AND PREGNANCY (27-28 June 2016, RIGA, LATVIA)
27-28 June 2016, Riga, Latvia hosted the International WHO consultation on nutrition and pregnancy, with participation of experts in the field of maternal and child health and the WHO Collaborating Centers from Poland, Latvia, Lithuania, Estonia, Italy, the UK, Kazakhstan, Tajikistan, Uzbekistan, Kyrgyzstan, Georgia, Armenia and Moldova. The key problems of women's health and nutrition, according to speakers from different countries are the following: the growth of overweight and obesity among women, excessive weight gain during pregnancy, low rates of exclusive breastfeeding in the first ...
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2016 жыл | Шығарылым: 4 | Беттер: 166-172