ПРОБЛЕМА АНТИБИОТИКОРЕЗИСТЕНТНОСТИ ОСНОВНЫХ ВОЗБУДИТЕЛЕЙ ВНЕБОЛЬНИЧНОЙ ПНЕВМОНИИ И ПУТИ ЕЕ ПРЕОДОЛЕНИЯ
В статье представлены результаты бактериологического исследования мокроты и определения чувствительности возбудителей внебольничной пневмонии у пациентов пульмонологического отделения. Описаны причины развития антибиотикорезистентности и современные методы комбинированной антибиотикотерапии внебольничной пневмонии.
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 57-59
ЭФФЕКТИВНОСТЬ ПРИМЕНЕНИЯ ФРОМИЛИД УНО ПРИ ИНФЕКЦИЯХ ВЕРХНИХ И НИЖНИХ ДЫХАТЕЛЬНЫХ ПУТЕЙ
Длительный опыт клинического использования свидетельствует о том, что Фромилид УНО (кларитромицин) за-нимает одно из важных мест в терапии острых и хронических инфекций верхних и нижних дыхательных путей и ак-туальность его применения возрастает с получением новых сведений об эффектах этого антибактериального пре-парата. Подтверждена высокая эффективность и безопасность препарата Фромилид УНО при лечении пациентов с острыми и хроническими инфекционно-воспалительными заболеваниями верхних и нижних дыхательных путей. Дозирование препарата один раз в сутки создает высокий комплаенс, миним...
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 55-57
ЭФФЕКТИВНОСТЬ ЛЕЧЕНИЯ НОВЫХ СЛУЧАЕВ ТУБЕРКУЛЕЗА ОРГАНОВ ДЫХАНИЯ
В статье проанализированы основные причины низкой эффективности лечения впервые выявленных больных. Невыполнение протокола диагностического алгоритма общей лечебной сетью привело к распространенным процес-сам, явившимся причиной смерти в 5 (2,8%) случаях. Поздняя обращаемость населения за медицинской помощью и высокий показатель МЛУ ТБ составил 13,7%.
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 53-54
ВЫДЕЛЕНИЕ И ОЧИСТКА НУКЛЕИНОВЫХ КИСЛОТ. СОСТОЯНИЕ ПРОБЛЕМЫ НА СОВРЕМЕННОМ ЭТАПЕ
В статье представлены стандартные и инновационные методы выделения ДНК, указаны преимущества и недо-статки различных способов экстракции ДНК. Описана качественная и количественная оценка нуклеиновых кислот для получения наиболее полноценной ДНК, позволяющая потом ее использовать в широком диапазоне научных исследований.
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 51-53
СРАВНИТЕЛЬНАЯ ОЦЕНКА КАЧЕСТВА ЖИЗНИ ПАЦИЕНТОВ С ЛЯМБЛИОЗОМ НА ФОНЕ РАЗЛИЧНЫХ РЕЖИМОВ ТЕРАПИИ
Проводилось открытое рандомизированное контролируемое исследование с участием 40 пациентов с целью сравнительного анализа изменений уровня качества жизни пациентов с лямблиозом на фоне терапии метронидазолом и комбинации метронидазола и саусалина. Оценка качества жизни проводилась с использованием русифицированной версии стандартизированного специализированного опросника Gastrointestinal Symptom Rating Scale. Было выявлено, достоверное снижение качества жизни респондентов за счет проявлений диспептического и болевого синдромов преимущественно в группе, получающей монотерапию метрони...
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 48-50
ШАШЫРАНДЫ СКЛЕРОЗБЕН НАУҚАСТАРДА ДЖОН КАННИНГЕМ ВИРУСЫНА ҚАРСЫ АНТИДЕНЕЛЕРДІҢ ТАРАЛУЫН АНЫҚТАУ – ОСЫ ДЕРТ КЕЗІНДЕГІ ҮДЕМЕЛІ МУЛЬТИФОКАЛЬДЫ ЛЕЙКОЭНЦЕФАЛОПАТИЯ ҚАУІП –ҚАТЕРІНІҢ СТРАТИФИКАЦИЯСЫ РЕТІНДЕ
2020 жыл | Шығарылым: 1 | Беттер: 64-71
ЖЕДЕЛ КОРОНАРЛЫҚ СИНДРОМ ДИАГНОЗЫ БАР ПАЦИЕНТТЕРДІ РЕТРОСПЕКТИВТІ БАҒАЛАУ
2020 жыл | Шығарылым: 1 | Беттер: 58-63
ҚАЗАҚСТАНДАҒЫ ЖЕКЕ АДАМДАРДЫҢ ІШЕК МИКРОБТЫҚ ҚАУЫМДАСТЫҒЫН МЕТАГЕНОМИКАЛЫҚ ТАЛДАУ
2020 жыл | Шығарылым: 1 | Беттер: 48-57
АЛЛЕРГИЯЛЫҚ РИНИТІ БАР ЕМДЕЛУШІЛЕРДЕ ЭОЗИНОФИЛЬДІ КАТИОНДЫ АҚУЫЗ
2020 жыл | Шығарылым: 1 | Беттер: 39-47
МЕДИЦИНАЛЫҚ БІЛІМДІ БАСҚАРУДЫҢ ӘДІСТЕРІН ЖЕТІЛДІРУ. ӘДЕБИЕТТІ ШОЛУ
2020 жыл | Шығарылым: 1 | Беттер: 27-38
COMPARATIVE EVALUATION OF PAIN SYNDROME OF OPERATED PATIENTS WITH INGUINAL HERNIAS
A comparative evaluation of operated patients with inguinal hernia in Medical Center Semey State Medical University fr om 2008 to 2015 year was performed. Patients of the main group were operated by our developed the method. The proposed method has advantages over traditional methods of plastics, is a universal intervention for large inguinal-scrotal and recurrent inguinal hernias. The technique allows to strengthen simultaneously the anterior and posterior wall of the inguinal canal, the inguinal ligament and the femoral canal, which leads to less pain in the postoperative period and the abse...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 93-102
EFFECT OF EXTRACT ON ACTIVITY OF ENERGY METABOLISM ENZYMES AFTER COMBINED EFFECT OF EMOTIONAL STRESS AND SUBLETHAL DOSE OF γ-RADIATION IN REMOTE PERIOD
Introduction. During adaptation process complex changes occur in metabolic pathways; functional and structural changes occur in organs and tissue. Despite the great interest of researchers to this problem, the pathogenetic mechanisms of influence of stress, especially combined effect of stressors on the metabolic processes hasn’t been studied enough. Main criterion for the stability of the adaptive behavior of the organism is to maintain energy potential of biosystems constant. Given the importance of this system, it is necessary to define its role in formation of pathological process in anima...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 67-78
THE FREQUENCY OF POLYMORPHISMS OF THE GENE 5382insC BRCA1 IN PATIENTS WITH FAMILIAL BREAST CANCERS ARE EXPOSED TO IONIZING RADIATION AS A RESULT OF SEMIPALATINSK NUCLEAR TEST SITE AND THEIR DESCENDANTS
Genetic changes play an important role among the risk factors for breast cancer, but their mechanisms of and contribution to the development of the disease is not finalized.
Purpose of the study: determining the frequency of the BRCA1 gene polymorphism 5382insC in patients with familial breast cancers in the region radiological trouble Semipalatinsk nuclear test site in the first and second generations of irradiated.
Materials and methods: The study included 250 women aged 40 to 79 years, Kazakh nationality, including 190 breast cancer patients, distributed in groups. The first gro... Толығырақ
Purpose of the study: determining the frequency of the BRCA1 gene polymorphism 5382insC in patients with familial breast cancers in the region radiological trouble Semipalatinsk nuclear test site in the first and second generations of irradiated.
Materials and methods: The study included 250 women aged 40 to 79 years, Kazakh nationality, including 190 breast cancer patients, distributed in groups. The first gro... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 58-66
FACTORS, ASSOCIATED WITH ONE YEAR SURVIVAL AFTER STROKE IN KAZAKHSTAN: A COHORT STUDY
Introduction. Many unresolved question exist about the predictors of stroke outcome. The evidence on the determinants of stroke survival in Kazakhstan is very scarce, despite the high prevalence of the problem.
The aim: To study factors associated with one -year stroke survival in a population of Semey, Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N = 937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests. Independent associations of the studied factors with survival were s... Толығырақ
The aim: To study factors associated with one -year stroke survival in a population of Semey, Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N = 937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests. Independent associations of the studied factors with survival were s... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 46-57
POLYMORPHISM OF IL10 GENE AT -1082G/A POSITION IN PATIENTS WITH ERYSIPELAS
The aim of this study is reveal the association of polymorphism of IL10 gene (rs1800896) at 1082 GA position with the erysipelas in Kazakh population.
Materials and methods. The polymorphism of IL10 gene (rs1800896) was assessed in 206 patients with erysipelas and 422 control subjects. Of them 143 patients with primary erysipelas and 63 with recurrence erysipelas. Genomic DNA was extracted from blood for genotyping. Genotyping of polymorphism of IL10 gene (-1082 GA) was conducted by method of polymerase chain reaction in real time. Pearson’s Chi tests ... Толығырақ
Materials and methods. The polymorphism of IL10 gene (rs1800896) was assessed in 206 patients with erysipelas and 422 control subjects. Of them 143 patients with primary erysipelas and 63 with recurrence erysipelas. Genomic DNA was extracted from blood for genotyping. Genotyping of polymorphism of IL10 gene (-1082 GA) was conducted by method of polymerase chain reaction in real time. Pearson’s Chi tests ... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 34-45