Проанализированы генетические варианты, выделенные из полных геномов и экзомов и показавшие ассоциацию с развитием гипертонии, ожирением и диабетом по обоим алгоритмическим предикторам патогенности мутаций PolyPhen2 и SIFT. Обнаружено семь генетических вариантов GHRL (rs4684677), MTHFR &... Толығырақ
Целью обзора было изучение исторических аспектов проблемы очищения кишечника, выбора оптимальных способов лаважа и переносимости его пациентами.
Методы исследования. В данном обзоре рассмотрена эффективность различных методов лаважа, подготовки больного перед эндоскопическим исследованием и операцией. Проведён анализ 77 литературных источников с результатами изучения данной проблемы.
Результаты. Си... Толығырақ
В последние годы активно изучается возможность применения витаминов группы В при сосудистых и ней родегенеративных заболеваниях. Дефицит витаминов В6, В12, В9, возникший в результате особенностей диеты и нарушения абсорбции, признан одним из основных факторов развития гипергомоцистеинемии. Установлено, что применение препа... Толығырақ
Background: Cervical cancer is one of the most common diseases of the female reproductive system. The annual increase in morbidity and mortality rates from this type of malignant neoplasm makes the problem of cervical cancer topical both in the whole world and in the Republic of Kazakhstan. The low survival rate for cervical cancer requires a detailed study of prevalence, epidemiology and mortality, which have different meanings both between countries and within the regions within t...
ТолығырақIn developed countries, endometrial cancer is the most common malignant gynecological disease with an average incidence of 14,7 per 100 000 women and is in the second place after cervical cancer. Worldwide, the average incidence in 2012 was 8,.2 per 100 000 women or 319 605 new cases of endometrial cancer with a combined risk of 0,97%. The countries with the highest morbidity rates per 100 000 women include Macedonia (29), Luxembourg (24,2), Czech Republic (17,97), Guyana (22,65), Serbia (17,8), Bulgaria (17,83) and the Russian Federation (16,2). At the same time, there is an extremely ...
ТолығырақPreventive health diagnosis is the basis of modern preventive medicine, and, in accordance with the recommendations of the World Health Organization, should be held annually. One of the components of the preventive medicine concept are Check up programs - a comprehensive examination and diagnosis of the body. Check up minimizes the impact of risk factors and allows you to detect the disease at the earliest stage of development, when it has not yet caused significant harm to the body.
An increasing number of patients in our country are applying for paid medical services for the p... Толығырақ
Relevance: Patella fractures are one of the least developed problems in modern traumatology and orthopedics. Despite the apparent simplicity of the principles of their treatment, complications and unfavorable results remain. The use of transosseous osteosynthesis appears to be an adequate treatment option.
Objective: To improve the method of transosseous osteosynthesis in patellar fractures and to evaluate the results of its application.
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